ADMA vs CSL: Which Is the Better Buy in 2026?
Last updated August 2026
Short answer
CSL is the larger of the two ($14.29B market cap): the incumbent the market prices for continued execution (15.05x forward earnings, beta 0.85). ADMA is the smaller challenger ($1.96B), cheaper on forward earnings (8.59x): more room to run, but more to prove. The real question is which set of drivers you believe, and whether owning one (or both) leaves you over-concentrated.
ADMA vs CSL: the tie-breaker metrics
Same yardstick, side by side (as of August 2026). Valuation lined up like this is most meaningful for two names in the same corner of the market, which these are. Figures are approximate; verify before investing.
| Metric | ADMA | CSL | What it tells you |
|---|---|---|---|
| Market cap | $1.96B | $14.29B | Size. The larger name is the incumbent; the smaller has more room to grow and more to prove. |
| Forward P/E | 8.59 | 15.05 | Valuation on next year's expected earnings, the same yardstick for both. Lower is cheaper for that growth; higher means the market is paying up. |
| Trailing P/E | 12.44 | 20.40 | Valuation on the last 12 months. A big drop from trailing to forward means the market expects earnings to jump, so more growth is already in the price. |
| Beta | 0.73 | 0.85 | Volatility vs the market. Above 1 swings harder than the index; below 1 is steadier. Higher beta means bigger drawdowns to hold through. |
| Price vs 52-week range | 9% of range | 48% of range | Where today's price sits between the 52-week low and high. Near the high is momentum with less margin of safety; near the low is out of favor or a discount, depending on why. |
| Price / book | 5.04 | 8.80 | How much you pay over book value. Very high can signal an asset-light, high-return business or a rich price. |
Reading it: ADMA is the cheaper of the two on forward earnings, but cheaper is not the same as better. Pair the valuation with growth (how far the forward P/E sits below the trailing P/E) and risk (beta) before you decide.
Before you buy: how ADMA and CSL affect your concentration
The metrics above tell you which is the marginally better business. The bigger risk for most people is not picking the slightly worse stock, it is over-concentrating. ADMA and CSL share themes, so owning both, or adding either to what you already hold, can quietly push a large share of your portfolio into one bet.
This is the part a generic comparison page cannot answer, because it depends on what you own. Connect your brokerage and Walnut shows your real, combined ADMA and CSL exposure, flags overlap with your existing positions, and tells you if adding one would tip you past a concentration you are comfortable with, read-only by default, with your login staying at your broker. Walnut is not an investment adviser.
What does ADMA Biologics (ADMA) do?
ADMA Biologics is an end-to-end biopharmaceutical company focused on plasma-derived therapies. It develops, manufactures, and markets immunoglobulin (IG) products and operates its own plasma-collection centers, giving it control over part of the supply chain that feeds its manufacturing. Its FDA-approved products include Asceniv, an intravenous immune globulin used to treat primary immunodeficiency, Bivigam, a standard intravenous immune globulin, and Nabi-HB for hepatitis B exposure. Asceniv is the company's differentiated, higher-value product and has been the main growth driver, while Bivigam competes in the more crowded standard-IG market.
What does Carlisle Companies Incorporated (CSL) do?
Carlisle Companies Incorporated (NYSE: CSL) is a diversified manufacturer that, after years of portfolio reshaping, has become a focused supplier of building-envelope products that make commercial and residential buildings more energy efficient. It operates through two segments: Carlisle Construction Materials (CCM), which makes single-ply roofing membranes (EPDM rubber, TPO, and PVC), polyiso insulation, and metal roofing and wall systems, and Carlisle Weatherproofing Technologies (CWT), which makes waterproofing, air and vapor barriers, sealants, spray polyurethane foam, coatings, and related moisture-protection products. The company earns most of its revenue from commercial construction, and within that, a large share comes from re-roofing (replacing aging roofs), which is more stable than new construction because roofs wear out on a predictable cycle regardless of the economy.
ADMA vs CSL: how do they differ?
Both fit overlapping themes, but they are not interchangeable. The useful comparison is which set of drivers and risks you want exposure to.
- ADMA drivers: Asceniv, the specialty growth driver; Integrated plasma-collection model.
- CSL drivers: Commercial re-roofing replacement cycle; Margin expansion and pure-play focus.
Which fits which kind of investor
A faster-growing, richer-valued name usually swings harder, so it suits a longer horizon and a higher tolerance for volatility; a steadier, more cash-generative business suits a more conservative or income-minded investor. The honest test is which set of risks you could hold through a drawdown: The dominant near-term risk is competition and pricing pressure in the standard immunoglobulin market, which drove a 54% drop in Bivigam revenue and led ADMA in 2026 to cut full-year guidance, reduce its net-income outlook, and withdraw long-term targets, citing rapidly evolving competitive dynamics. For CSL, carlisle's end markets are cyclical: commercial and residential construction activity is sensitive to interest rates, credit availability, and the broader economy, and a downturn in construction spending would pressure volumes.
ADMA or CSL: which should you pick?
Growth-minded investors who believe the theme has years to run tend to accept the richer multiple for more upside; value-minded investors lean toward the cheaper forward earnings and steadier profile. Pick ADMA if you believe its drivers more; CSL if you believe its. Many investors hold both, but since they share themes, that is a concentrated bet, not diversification. Decide deliberately and check overlap. For the full detail, see the ADMA and CSL guides.
ADMA vs CSL: the full fundamentals
ADMA. Figures are approximate and tied to the asOf date; verify live numbers before acting. ADMA is profitable, so an earnings multiple is meaningful, but the 2026 guidance cut and withdrawn long-term targets make forward estimates less certain than before, so investors should weigh the durability of Asceniv growth against standard-IG competition rather than rely on a single multiple. The mix shift toward specialty product matters more here than headline revenue, which stayed flat.
CSL. Carlisle trades around a low-20s trailing P/E, roughly in line with its own long-term historical median and typical for a high-margin, cash-generative industrial. Because a large part of its earnings power comes from resilient re-roofing demand and steady margin expansion, investors tend to focus on adjusted EBITDA margin, free cash flow, and the pace of buybacks rather than raw revenue growth, which can be lumpy with weather and construction cycles. The Q1 2026 revenue dip was driven largely by poor winter weather that limited roofing installation, while margins still expanded and management reaffirmed full-year guidance for low-single-digit revenue growth.
Headline figures (approximate, Jul 2026): ADMA shows revenue (q1 2026) ~$114.5 million, roughly flat year over year, eps (q1 2026) ~$0.19, up about 73% year over year, product mix trend Asceniv revenue up ~28%; Bivigam down ~54%, 2026 revenue guidance cut to ~$530 to $560 million (from a prior view above $635 million); CSL shows revenue (ttm) ~$5.0 billion, q1 2026 revenue ~$1.05 billion (down ~4% year over year), q1 2026 adjusted eps ~$3.63 (up ~1% year over year), q1 2026 adjusted ebitda margin ~22.3% (up ~50 bps).
The bottom line: ADMA vs CSL
ADMA and CSL are related but distinct: same themes, different businesses and risks. Neither wins in the abstract; the right pick is whichever thesis you actually believe, sized so you are not over-concentrated in one theme. Walnut can show your combined ADMA and CSL exposure against your real portfolio. It is not an investment adviser.
Wondering how ADMA or CSL fits the portfolio you already own? Walnut is an AI investing app that connects your brokerage read-only and answers questions like that about your actual holdings: overlap, concentration, and how each position tracks the S&P 500. Compare the best AI portfolio analyzers or see the best AI investing apps in 2026.
Investing in ADMA Biologics with AI
Connect the broker you already use and ask Walnut's AI how ADMA fits what you actually hold: whether you own it already through a fund, what it would do to your concentration, and how it has tracked the S&P 500. Read-only by default, and you approve anything before it reaches your broker.
FAQ
What is the difference between ADMA and CSL?
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ADMA Biologics is an end-to-end biopharmaceutical company focused on plasma-derived therapies. Carlisle Companies Incorporated (NYSE: CSL) is a diversified manufacturer that, after years of portfolio reshaping, has become a focused supplier of building-envelope products that make commercial and residential buildings more energy efficient. They show up together because they share investment themes, but they are different businesses, so the better fit depends on which thesis you are expressing.
Is ADMA or CSL the better stock?
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Neither is universally better. CSL is the larger incumbent; ADMA is the smaller challenger and looks cheaper on forward earnings. Walnut is informational, not investment advice. Compare what each does, the tie-breaker metrics above, and the risks, then decide which fits your thesis and what you already own.
Which is cheaper, ADMA or CSL?
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On forward P/E (as of August 2026), ADMA trades at 8.59x and CSL at 15.05x, so ADMA is the cheaper of the two on next year's expected earnings. A lower multiple is not automatically the better buy: a richer valuation can be justified by faster growth, and a lower one can reflect real risk. Weigh the multiple against how fast each business is compounding.
Should you own both ADMA and CSL?
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Because they share themes, owning both concentrates you in that theme. That can be intentional (a focused bet) or accidental (less diversification than it looks). Walnut can show your combined exposure across both, and whether adding either over-concentrates you, before you buy.
What are the risks of ADMA vs CSL?
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ADMA: The dominant near-term risk is competition and pricing pressure in the standard immunoglobulin market, which drove a 54% drop in Bivigam revenue and led ADMA in 2026 to cut full-year guidance, reduce its net-income outlook, and withdraw long-term targets, citing rapidly evolving competitive dynamics. Elevated channel inventories can delay a recovery in standard-IG sales. Concentration risk is real: growth now leans heavily on a single specialty product, Asceniv, so any stumble there would weigh disproportionately. Plasma-derived manufacturing depends on collecting enough specialized plasma and on regulatory compliance, so supply or FDA issues could disrupt output. As a relatively small biopharma, ADMA is more exposed to single-product and single-market shocks than a diversified drugmaker, and its shares have been volatile, falling sharply after the guidance change. Larger, better-resourced plasma competitors can sustain price competition longer than ADMA. CSL: Carlisle's end markets are cyclical: commercial and residential construction activity is sensitive to interest rates, credit availability, and the broader economy, and a downturn in construction spending would pressure volumes. Revenue can swing on weather, as seen in Q1 2026 when unfavorable winter conditions limited contractors' days on the roof and helped push revenue down about 4% year over year. The business is exposed to raw-material and energy cost inflation (chemicals, membranes, insulation feedstocks) and to destocking or restocking cycles in its distribution channel that can amplify demand swings. Competition in single-ply roofing is intense, with large rivals such as Holcim (owner of Firestone and Duro-Last), GAF, and Johns Manville. Finally, much of Carlisle's growth story depends on continued margin expansion and disciplined capital allocation, so any slippage in pricing power or a misstep in M&A could weigh on the shares.
Walnut is informational, not investment advice. This page is descriptive and not a recommendation to buy or sell ADMA or CSL; figures are approximate and dated (as of August 2026). Verify current data before investing.