BFLY vs TMDX: Which Is the Better Buy in 2026?

Last updated August 2026

Short answer

TMDX is the larger of the two ($2.64B market cap): the incumbent the market prices for continued execution (26.68x forward earnings, beta 1.88). BFLY is the smaller challenger ($1.89B), priced similarly on forward earnings (-86.18x): more room to run, but more to prove. The real question is which set of drivers you believe, and whether owning one (or both) leaves you over-concentrated.

BFLY vs TMDX: the tie-breaker metrics

Same yardstick, side by side (as of August 2026). Valuation lined up like this is most meaningful for two names in the same corner of the market, which these are. Figures are approximate; verify before investing.

MetricBFLYTMDXWhat it tells you
Market cap$1.89B$2.64BSize. The larger name is the incumbent; the smaller has more room to grow and more to prove.
Forward P/E-86.1826.68Valuation on next year's expected earnings, the same yardstick for both. Lower is cheaper for that growth; higher means the market is paying up.
Beta2.051.88Volatility vs the market. Above 1 swings harder than the index; below 1 is steadier. Higher beta means bigger drawdowns to hold through.
Price vs 52-week range69% of range17% of rangeWhere today's price sits between the 52-week low and high. Near the high is momentum with less margin of safety; near the low is out of favor or a discount, depending on why.
Price / book9.715.35How much you pay over book value. Very high can signal an asset-light, high-return business or a rich price.

Before you buy: how BFLY and TMDX affect your concentration

The metrics above tell you which is the marginally better business. The bigger risk for most people is not picking the slightly worse stock, it is over-concentrating. BFLY and TMDX share themes, so owning both, or adding either to what you already hold, can quietly push a large share of your portfolio into one bet.

This is the part a generic comparison page cannot answer, because it depends on what you own. Connect your brokerage and Walnut shows your real, combined BFLY and TMDX exposure, flags overlap with your existing positions, and tells you if adding one would tip you past a concentration you are comfortable with, read-only by default, with your login staying at your broker. Walnut is not an investment adviser.

What does Butterfly Network (BFLY) do?

Butterfly Network designs and sells handheld ultrasound systems built on its proprietary Ultrasound-on-Chip technology, which replaces the traditional piezoelectric crystals in an ultrasound machine with a semiconductor sensor. That lets a single probe (the flagship iQ3) image the whole body and connect to a phone or tablet, and the company layers on subscription software, cloud storage, and AI tools that push clinicians toward higher-margin recurring revenue. Customers include hospitals, clinics, medical schools, and increasingly international and lower-resource settings where a $2,000-to-$5,000-range device is far cheaper than a cart-based system.

Full BFLY guide

What does TransMedics Group (TMDX) do?

TransMedics Group is a commercial-stage medical-technology company built around the Organ Care System (OCS), a portable device that perfuses donor organs with warm oxygenated blood to keep them functioning and assessable outside the body, an alternative to keeping organs on ice. It has FDA approval for OCS Heart, OCS Liver, and OCS Lung, including organs recovered from donors after circulatory death (DCD), which meaningfully expands the pool of usable organs. On top of the devices, TransMedics has built a National OCS Program (NOP) that provides organ retrieval surgeons, ground transport, and a growing owned aviation fleet, so the company now earns both product revenue from disposables and service revenue from logistics.

Full TMDX guide

BFLY vs TMDX: how do they differ?

Both fit overlapping themes, but they are not interchangeable. The useful comparison is which set of drivers and risks you want exposure to.

  • BFLY drivers: Software and recurring-revenue mix shift; iQ3 probe and hardware refresh cycle.
  • TMDX drivers: OCS adoption and DCD organ expansion; National OCS Program and owned logistics.

Which fits which kind of investor

A faster-growing, richer-valued name usually swings harder, so it suits a longer horizon and a higher tolerance for volatility; a steadier, more cash-generative business suits a more conservative or income-minded investor. The honest test is which set of risks you could hold through a drawdown: Butterfly remains unprofitable, with trailing losses of roughly $76M against about $103M of revenue as of Q1 2026, so it depends on its cash balance and, potentially, future capital raises that could dilute shareholders. For TMDX, transMedics depends heavily on the OCS platform and its National OCS Program, so any slowdown in transplant volumes, reimbursement changes, or clinical setbacks would hit results directly.

BFLY or TMDX: which should you pick?

Growth-minded investors who believe the theme has years to run tend to accept the richer multiple for more upside; value-minded investors lean toward the cheaper forward earnings and steadier profile. Pick BFLY if you believe its drivers more; TMDX if you believe its. Many investors hold both, but since they share themes, that is a concentrated bet, not diversification. Decide deliberately and check overlap. For the full detail, see the BFLY and TMDX guides.

BFLY vs TMDX: the full fundamentals

BFLY. As of mid-2026, Butterfly generated roughly $103M in trailing revenue while posting net losses, and it guided to full-year 2026 revenue of about $117M to $121M with an adjusted-EBITDA loss of roughly $21M to $25M. With a market cap in the $1.5B-to-$2.3B range after a large share-price run, the stock trades at a high multiple of sales, so the valuation embeds substantial future growth. The roughly $138M cash balance gives it a multi-year runway at current burn rates.

TMDX. TransMedics traded around $76 in mid-July 2026, well below its 52-week high near $156 and closer to its low around $60, reflecting a large re-rating after margin pressure and earnings misses. The company remains profitable but thinly so, which makes valuation multiples sensitive to which earnings measure is used. The stock is priced as a high-growth medical-technology name, so continued 20%-plus revenue growth is largely an expectation rather than a cushion.

Headline figures (approximate, JUNE 2026): BFLY shows revenue (ttm) ~$103M, q1 2026 revenue growth ~25% YoY, fy2026 revenue guidance ~$117M to $121M, gross margin (q1 2026) ~69%; TMDX shows revenue (ttm) ~$636M, q1 2026 revenue ~$173.9M (+21% YoY), fy2026 revenue guidance ~$727M to $757M (20-25% growth), q1 2026 gross margin ~58% (down from ~61%).

The bottom line: BFLY vs TMDX

BFLY and TMDX are related but distinct: same themes, different businesses and risks. Neither wins in the abstract; the right pick is whichever thesis you actually believe, sized so you are not over-concentrated in one theme. Walnut can show your combined BFLY and TMDX exposure against your real portfolio. It is not an investment adviser.

Wondering how BFLY or TMDX fits the portfolio you already own? Walnut is an AI investing app that connects your brokerage read-only and answers questions like that about your actual holdings: overlap, concentration, and how each position tracks the S&P 500. Compare the best AI portfolio analyzers or see the best AI investing apps in 2026.

Investing in Butterfly Network with AI

Connect the broker you already use and ask Walnut's AI how BFLY fits what you actually hold: whether you own it already through a fund, what it would do to your concentration, and how it has tracked the S&P 500. Read-only by default, and you approve anything before it reaches your broker.

FAQ

What is the difference between BFLY and TMDX?

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Butterfly Network designs and sells handheld ultrasound systems built on its proprietary Ultrasound-on-Chip technology, which replaces the traditional piezoelectric crystals in an ultrasound machine with a semiconductor sensor. TransMedics Group is a commercial-stage medical-technology company built around the Organ Care System (OCS), a portable device that perfuses donor organs with warm oxygenated blood to keep them functioning and assessable outside the body, an alternative to keeping organs on ice. They show up together because they share investment themes, but they are different businesses, so the better fit depends on which thesis you are expressing.

Is BFLY or TMDX the better stock?

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Neither is universally better. TMDX is the larger incumbent; BFLY is the smaller challenger and looks cheaper on forward earnings. Walnut is informational, not investment advice. Compare what each does, the tie-breaker metrics above, and the risks, then decide which fits your thesis and what you already own.

Which is cheaper, BFLY or TMDX?

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On forward P/E (as of August 2026), BFLY trades at -86.18x and TMDX at 26.68x, so BFLY is the cheaper of the two on next year's expected earnings. A lower multiple is not automatically the better buy: a richer valuation can be justified by faster growth, and a lower one can reflect real risk. Weigh the multiple against how fast each business is compounding.

Should you own both BFLY and TMDX?

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Because they share themes, owning both concentrates you in that theme. That can be intentional (a focused bet) or accidental (less diversification than it looks). Walnut can show your combined exposure across both, and whether adding either over-concentrates you, before you buy.

What are the risks of BFLY vs TMDX?

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BFLY: Butterfly remains unprofitable, with trailing losses of roughly $76M against about $103M of revenue as of Q1 2026, so it depends on its cash balance and, potentially, future capital raises that could dilute shareholders. The point-of-care ultrasound market is competitive, with GE HealthCare, Philips, Clarius, Exo, and others fielding rival handheld devices, which can pressure pricing and adoption. Revenue is lumpy because it leans on hardware launch cycles and large institutional orders, and the stock trades at a high multiple of sales after a large run-up, leaving it vulnerable to sharp drawdowns if growth or margins disappoint. Regulatory, reimbursement, and clinical-adoption dynamics add further uncertainty to the timeline for profitability. TMDX: TransMedics depends heavily on the OCS platform and its National OCS Program, so any slowdown in transplant volumes, reimbursement changes, or clinical setbacks would hit results directly. Margins have compressed as the company spends aggressively on logistics, aviation, and research, and quarterly adjusted earnings have missed analyst expectations, contributing to a sharp drop from 2025 highs. The company has flagged an identified material weakness in internal controls in past filings and carries 1.50% convertible notes due 2028 that add financing risk. Its growing dominance in organ perfusion could invite antitrust or competitive scrutiny, and next-generation products like OCS Kidney face clinical-trial and regulatory uncertainty. The stock is volatile and richly valued relative to current earnings, so disappointments can trigger large moves.

Walnut is informational, not investment advice. This page is descriptive and not a recommendation to buy or sell BFLY or TMDX; figures are approximate and dated (as of August 2026). Verify current data before investing.

    BFLY vs TMDX: Which Is the Better Buy in 2026? - Walnut AI Investing App