DNA vs RXRX: Which Is the Better Buy in 2026?

Last updated August 2026

Short answer

RXRX is the larger of the two ($1.59B market cap): the incumbent the market prices for continued execution (-3.19x forward earnings, beta 1.00). DNA is the smaller challenger ($528.48M), priced similarly on forward earnings (-2.52x): more room to run, but more to prove. The real question is which set of drivers you believe, and whether owning one (or both) leaves you over-concentrated.

DNA vs RXRX: the tie-breaker metrics

Same yardstick, side by side (as of August 2026). Valuation lined up like this is most meaningful for two names in the same corner of the market, which these are. Figures are approximate; verify before investing.

MetricDNARXRXWhat it tells you
Market cap$528.48M$1.59BSize. The larger name is the incumbent; the smaller has more room to grow and more to prove.
Forward P/E-2.52-3.19Valuation on next year's expected earnings, the same yardstick for both. Lower is cheaper for that growth; higher means the market is paying up.
Beta1.781.00Volatility vs the market. Above 1 swings harder than the index; below 1 is steadier. Higher beta means bigger drawdowns to hold through.
Price vs 52-week range22% of range5% of rangeWhere today's price sits between the 52-week low and high. Near the high is momentum with less margin of safety; near the low is out of favor or a discount, depending on why.
Price / book1.131.55How much you pay over book value. Very high can signal an asset-light, high-return business or a rich price.

Before you buy: how DNA and RXRX affect your concentration

The metrics above tell you which is the marginally better business. The bigger risk for most people is not picking the slightly worse stock, it is over-concentrating. DNA and RXRX share themes, so owning both, or adding either to what you already hold, can quietly push a large share of your portfolio into one bet.

This is the part a generic comparison page cannot answer, because it depends on what you own. Connect your brokerage and Walnut shows your real, combined DNA and RXRX exposure, flags overlap with your existing positions, and tells you if adding one would tip you past a concentration you are comfortable with, read-only by default, with your login staying at your broker. Walnut is not an investment adviser.

What does Ginkgo Bioworks Holdings (DNA) do?

Ginkgo Bioworks Holdings, Inc. (NYSE: DNA) is a synthetic-biology company built around a horizontal cell-programming platform. Historically it reported in two segments: Cell Engineering, where its automated Foundry labs and Datapoints data service engineer and characterize cells for pharma, agriculture, food, and industrial customers; and Biosecurity, which provided pathogen monitoring and bioinformatics to governments and institutions. Cell Engineering revenue is generated through R&D service fees, its Datapoints biological-data offerings, and design, build, and support fees for its lab-automation (RAC) systems. Ginkgo went public via SPAC in 2021 at a lofty valuation that has since collapsed.

Full DNA guide

What does Recursion Pharmaceuticals (RXRX) do?

Recursion Pharmaceuticals is a Salt Lake City-based, clinical-stage technology-enabled biopharmaceutical company that aims to industrialize drug discovery. Its platform combines automated wet-lab biology, high-throughput cellular imaging that generates petabytes of proprietary experimental data, and machine-learning models that map relationships between genes, compounds, and disease, layered with Exscientia's automated precision molecular design. Recursion intends to make money three ways: partnership and collaboration payments (upfront fees, research funding, and milestone payments from large pharma companies that use its platform), future royalties on any partnered drugs that reach market, and value from its own wholly owned pipeline of clinical candidates. Today the company is pre-revenue in the product sense: reported revenue is small (roughly $6.5 million in Q1 2026) and comes mostly from partnerships rather than drug sales.

Full RXRX guide

DNA vs RXRX: how do they differ?

Both fit overlapping themes, but they are not interchangeable. The useful comparison is which set of drivers and risks you want exposure to.

  • DNA drivers: AI, autonomous labs, and Datapoints; Cost restructuring toward breakeven.
  • RXRX drivers: An industrial-scale AI platform and proprietary data moat; A deep big-pharma partnership book.

Which fits which kind of investor

A faster-growing, richer-valued name usually swings harder, so it suits a longer horizon and a higher tolerance for volatility; a steadier, more cash-generative business suits a more conservative or income-minded investor. The honest test is which set of risks you could hold through a drawdown: The dominant risk is cash burn against an uncertain path to profitability: Ginkgo remains deeply unprofitable, revenue has kept falling year over year, and it is spending down its cash while promising breakeven that has not yet arrived. For RXRX, the central risk is that Recursion has no approved drug and remains deeply unprofitable, posting a net loss of roughly $117.5 million in Q1 2026 against only about $6.5 million of revenue, so the entire valuation rests on platform promise rather than proven output.

DNA or RXRX: which should you pick?

Growth-minded investors who believe the theme has years to run tend to accept the richer multiple for more upside; value-minded investors lean toward the cheaper forward earnings and steadier profile. Pick DNA if you believe its drivers more; RXRX if you believe its. Many investors hold both, but since they share themes, that is a concentrated bet, not diversification. Decide deliberately and check overlap. For the full detail, see the DNA and RXRX guides.

DNA vs RXRX: the full fundamentals

DNA. These are qualitative descriptions, not precise figures, and they are tied to the asOf date; verify live numbers before acting. Traditional earnings multiples do not apply to Ginkgo because it is unprofitable, so what matters is the trajectory of revenue, losses, cash burn, and progress toward the stated breakeven target. Because the company is pre-profit and pivoting its model, its valuation reflects belief in a future that has not yet been proven.

RXRX. Because Recursion is pre-profit with minimal revenue, traditional earnings multiples do not apply, and the figures that matter most are cash on hand, the rate of cash burn, and how long the runway lasts before the company must raise money again. Q1 2026 showed narrower losses driven by sizable cuts to R&D and overhead, which extended the stated runway into early 2028, but revenue came in well below analyst expectations. For a story like this, valuation is ultimately a bet on future platform output and partnership milestones rather than on current financial performance.

Headline figures (approximate, Jul 2026): DNA shows revenue (ttm) Small and declining; Cell Engineering revenue fell year over year, and recent quarterly revenue dropped sharply versus the prior-year period, net loss / adjusted ebitda Still loss-making; large GAAP net losses continue, though narrower than before, with adjusted-EBITDA breakeven targeted by end of 2026, cash position Several hundred million dollars in cash and marketable securities, funding operations while the company burns cash under its restructuring plan, path to profitability Management guides to adjusted-EBITDA breakeven by the end of 2026 via cost cuts; sustained GAAP profitability is not yet in sight; RXRX shows revenue (q1 2026) ~$6.5 million (mostly partnership and milestone revenue, missed analyst estimates), net loss (q1 2026) ~$117.5 million (narrowed from the prior year on cost cuts), cash and investments ~$665 million (as of March 31, 2026), guided 2026 operating cash burn less than ~$390 million; stated runway into early 2028 without new financing.

The bottom line: DNA vs RXRX

DNA and RXRX are related but distinct: same themes, different businesses and risks. Neither wins in the abstract; the right pick is whichever thesis you actually believe, sized so you are not over-concentrated in one theme. Walnut can show your combined DNA and RXRX exposure against your real portfolio. It is not an investment adviser.

Wondering how DNA or RXRX fits the portfolio you already own? Walnut is an AI investing app that connects your brokerage read-only and answers questions like that about your actual holdings: overlap, concentration, and how each position tracks the S&P 500. Compare the best AI portfolio analyzers or see the best AI investing apps in 2026.

Investing in Ginkgo Bioworks Holdings with AI

Connect the broker you already use and ask Walnut's AI how DNA fits what you actually hold: whether you own it already through a fund, what it would do to your concentration, and how it has tracked the S&P 500. Read-only by default, and you approve anything before it reaches your broker.

FAQ

What is the difference between DNA and RXRX?

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Ginkgo Bioworks Holdings, Inc. Recursion Pharmaceuticals is a Salt Lake City-based, clinical-stage technology-enabled biopharmaceutical company that aims to industrialize drug discovery. They show up together because they share investment themes, but they are different businesses, so the better fit depends on which thesis you are expressing.

Is DNA or RXRX the better stock?

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Neither is universally better. RXRX is the larger incumbent; DNA is the smaller challenger and looks pricier on forward earnings. Walnut is informational, not investment advice. Compare what each does, the tie-breaker metrics above, and the risks, then decide which fits your thesis and what you already own.

Which is cheaper, DNA or RXRX?

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On forward P/E (as of August 2026), DNA trades at -2.52x and RXRX at -3.19x, so RXRX is the cheaper of the two on next year's expected earnings. A lower multiple is not automatically the better buy: a richer valuation can be justified by faster growth, and a lower one can reflect real risk. Weigh the multiple against how fast each business is compounding.

Should you own both DNA and RXRX?

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Because they share themes, owning both concentrates you in that theme. That can be intentional (a focused bet) or accidental (less diversification than it looks). Walnut can show your combined exposure across both, and whether adding either over-concentrates you, before you buy.

What are the risks of DNA vs RXRX?

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DNA: The dominant risk is cash burn against an uncertain path to profitability: Ginkgo remains deeply unprofitable, revenue has kept falling year over year, and it is spending down its cash while promising breakeven that has not yet arrived. If losses persist, further capital raises could dilute existing shareholders, and the company already completed a 1-for-40 reverse split after its post-SPAC valuation collapsed by billions, a reminder of how far expectations have reset. Customer concentration is a concern because a handful of large partners can drive results, and losing or delaying programs hits revenue hard. Competition spans synthetic-biology, lab-automation, and bio-AI players with more focus or funding. Execution risk on the autonomous-lab pivot is high, and the stock is speculative and volatile, so outcomes could be very good or very poor. RXRX: The central risk is that Recursion has no approved drug and remains deeply unprofitable, posting a net loss of roughly $117.5 million in Q1 2026 against only about $6.5 million of revenue, so the entire valuation rests on platform promise rather than proven output. AI-driven drug discovery as a category is still unproven at the finish line, and skeptics note that no AI-originated compound has yet delivered a blockbuster approval, leaving open the possibility that the platform advantage does not translate into clinical success. Recursion's Phase 2 candidates could fail in trials like most clinical-stage biotech assets do, and even partnered programs depend on decisions outside Recursion's control. Although the company guides to a cash runway into early 2028, continued losses mean it may need to raise capital again, and equity raises would dilute existing shareholders; the stock has also been volatile, trading well below prior highs.

Walnut is informational, not investment advice. This page is descriptive and not a recommendation to buy or sell DNA or RXRX; figures are approximate and dated (as of August 2026). Verify current data before investing.

    DNA vs RXRX: Which Is the Better Buy in 2026? - Walnut AI Investing App