Supernus Pharmaceuticals, Inc. (SUPN) Stock Price & How to Invest
Last updated July 2026
Short answer
Supernus Pharmaceuticals (SUPN) is a mid-cap specialty pharma company built around central nervous system medicines, and the way to think about it is as a portfolio transition: four growth products (Qelbree, GOCOVRI, ZURZUVAE and ONAPGO) grew ~52% in the second quarter of 2026 and now carry the business while older epilepsy and Parkinson's franchises fade under generic pressure. Anyone looking at it today is also underwriting the announced all-stock merger of equals with Indivior, which would convert each Supernus share into 1.5401 Indivior shares and leave Supernus holders with roughly 43.5% of a combined ~$2.2 billion revenue CNS company.
SUPN stock price
As of 2026-08-04, Supernus Pharmaceuticals, Inc. (SUPN) last closed at $43.25, up 15.2% over the past year. Over the past 52 weeks it has traded between $37.53 and $57.00.
Prices are daily closing prices from Yahoo Finance and may be delayed. For the live quote, check your broker or Supernus Pharmaceuticals, Inc.'s investor relations page. Walnut is informational, not investment advice.
What does Supernus Pharmaceuticals, Inc. (SUPN) do?
Supernus Pharmaceuticals develops and sells prescription medicines for central nervous system conditions: ADHD, epilepsy, Parkinson's disease and, more recently, postpartum depression. The commercial model is straightforward specialty pharma. Supernus owns or licenses the products, runs its own US sales force calling on neurologists and psychiatrists, and books the revenue net of rebates and channel discounts. Its growth engine is Qelbree, a non-stimulant ADHD treatment that did ~$89 million in net sales in the second quarter of 2026 (up ~15%), alongside GOCOVRI for Parkinson's dyskinesia (~$38 million), ONAPGO, a continuous subcutaneous apomorphine infusion launched in 2025 (~$14 million), and collaboration revenue from ZURZUVAE for postpartum depression (~$35 million), which Supernus acquired when it bought Sage Therapeutics in mid-2025 and which it splits 50/50 with Biogen. Working against that are the legacy products: Trokendi XR and Oxtellar XR each fell ~25% year over year, APOKYN fell ~51%, and other older products fell ~71%.
The financial picture as of August 2026 is a company whose reported numbers and adjusted numbers say different things. Second-quarter revenue was ~$219 million, up ~32%, and management raised full-year 2026 guidance to ~$860 million to ~$890 million in revenue and ~$150 million to ~$180 million in adjusted operating earnings. On a GAAP basis the same quarter produced a ~$58 million net loss, driven by a ~$55 million non-cash impairment of the APOKYN intangible plus ~$25 million of ongoing intangible amortization, and the full-year GAAP outlook was cut to an operating loss of ~$20 million to ~$50 million. The balance sheet holds ~$372 million in cash and marketable securities with no meaningful debt at the Supernus level. On top of that sits the August 2026 agreement to merge with Indivior, maker of the opioid-use-disorder treatment SUBLOCADE, in an all-stock deal targeting ~$2.2 billion of combined revenue, ~$888 million of EBITDA and ~$125 million of annual cost synergies, with closing targeted for the fourth quarter of 2026.
What's driving Supernus Pharmaceuticals, Inc. (SUPN)?
1. Qelbree as the volume anchor in ADHD
Qelbree is the largest single product at ~$89 million in quarterly net sales and grew ~15% year over year. It is a non-stimulant, which gives it a distinct slot in a market still dominated by controlled-substance stimulants that face periodic supply and prescribing constraints. Growth has decelerated from the triple-digit rates of its launch years, so the question is whether it settles into steady mid-teens expansion or flattens as the addressable pool of stimulant-averse patients gets worked through.
2. ONAPGO and the device-delivered Parkinson's franchise
ONAPGO, approved in February 2025, is the first continuous subcutaneous apomorphine infusion cleared in the US for motor fluctuations in advancing Parkinson's. It reached ~$14 million in the quarter and guidance calls for ~$55 million to ~$70 million for the full year after supply constraints were resolved and new patient starts resumed. A regulatory submission for a second supplier was expected in the third quarter of 2026, with possible approval by mid-2027, which matters because single-source manufacturing is what interrupted the launch in the first place.
3. ZURZUVAE and the Sage acquisition
The July 2025 Sage acquisition brought ZURZUVAE, the only oral treatment approved for postpartum depression, into the portfolio. Supernus records 50% of Biogen's net revenue as collaboration revenue, which was ~$35 million in the quarter and carries no direct selling cost on the Supernus side. It is the highest-margin revenue line in the company and diversifies Supernus into neuropsychiatry, though it also means half the economics and none of the commercial control sit with a partner.
4. The Indivior merger of equals
The announced all-stock combination would exchange each Supernus share for 1.5401 Indivior shares, leaving Indivior holders with ~56.5% and Supernus holders with ~43.5% of a company targeting ~$2.2 billion in revenue and ~$125 million in annual cost synergies. Indivior brings SUBLOCADE and an opioid-use-disorder franchise, which is adjacent to but distinct from Supernus's neurology and psychiatry base. Indivior shareholders are also set to receive a ~$1 billion pre-closing special cash dividend funded in part by a ~$650 million term loan, so the combined entity would carry leverage that standalone Supernus does not.
What are the risks to Supernus Pharmaceuticals, Inc. (SUPN)?
The legacy portfolio is shrinking faster than it looks on a consolidated line: Trokendi XR and Oxtellar XR are guided to only ~$50 million to ~$60 million combined for 2026, APOKYN halved year over year and took a ~$55 million impairment, and every dollar lost there has to be replaced before growth shows up in total revenue. Qelbree's US new-chemical-entity exclusivity ran out in April 2026 and Supernus received Paragraph IV notices from multiple generic filers in 2025, so the patents running from 2029 to 2035 now have to be defended in court rather than assumed. The merger itself carries real execution risk: it requires shareholder and regulatory approvals, adds leverage through the pre-closing special dividend, and hands Supernus holders a minority position in a business whose largest product serves opioid use disorder, a category with its own reimbursement and legal history. GAAP profitability is currently negative and management's own guidance sees a full-year operating loss, so the ~12x forward earnings multiple rests on adjusted figures that exclude impairments and amortization. Pipeline outcomes have disappointed before, including the SPN-820 miss in treatment-resistant depression in early 2025, and SPN-817 and SPN-820 remain in Phase 2b.
What is the Supernus Pharmaceuticals, Inc. (SUPN) forecast?
4 analysts publish price targets on SUPN, averaging $62.50 against a $43.25 price as of August 2026, or +44.5%. The published targets run from $55.00 to $67.00, a narrow spread, and the ratings split 3 buy, 1 hold, 0 sell. Over the last six months there has been 1 raise and 0 cuts among the published actions. A price target is what an analyst published on a date, not a prediction, and sell-side ratings skew positive across the whole market.
Read the full SUPN forecast and price target for the target table, the recent rating actions by firm, and how the consensus has shifted.
Is SUPN a buy or a sell?
We give no verdict on Supernus Pharmaceuticals, Inc.. Both cases are real, which is why the question is contested at all, so here is the strongest version of each.
The case for buying. Qelbree as the volume anchor in ADHD. Qelbree is the largest single product at ~$89 million in quarterly net sales and grew ~15% year over year. The most optimistic published target, $67.00, assumes this works close to its best case.
The case against. The legacy portfolio is shrinking faster than it looks on a consolidated line: Trokendi XR and Oxtellar XR are guided to only ~$50 million to ~$60 million combined for 2026, APOKYN halved year over year and took a ~$55 million impairment, and every dollar lost there has to be replaced before growth shows up in total revenue. The most pessimistic target, $55.00, is roughly what SUPN is worth if this bites instead.
Read the full bull and bear case on SUPN, including what would have to change to break either one. Walnut is not an investment adviser.
How is Supernus Pharmaceuticals, Inc. (SUPN) valued? (approximate, August 2026)
A simple financial snapshot. These are approximations and refresh quarterly; for current figures see Supernus Pharmaceuticals, Inc.'s investor relations page or your broker.
- Revenue (TTM): ~$830M
- Q2 2026 revenue: ~$219M, up ~32% year over year
- FY2026 revenue guidance: ~$860M to ~$890M
- FY2026 adjusted operating earnings guidance: ~$150M to ~$180M
- Net income (TTM): ~-$110M, or ~-$1.91 per share
- Market cap / cash: ~$2.5B market cap, ~$372M cash and marketable securities, no meaningful debt
At ~$43 per share the market values Supernus at roughly 2.4 times enterprise value to 2026 guided revenue and about 12 times forward earnings, which is a discount to profitable specialty pharma peers and reflects both the legacy-product decay and the pending merger. The GAAP loss is largely non-cash: a ~$55 million APOKYN impairment and ~$25 million per quarter of intangible amortization from prior acquisitions sit between adjusted operating earnings of ~$31 million in the quarter and the reported ~$58 million net loss. Because the Indivior exchange ratio is fixed at 1.5401 shares, the practical value of a Supernus share now moves with Indivior's price as much as with Supernus's own results.
Who competes with Supernus Pharmaceuticals, Inc. (SUPN)?
ADHD treatments competing with Qelbree
Takeda (Vyvanse, now genericized), Tris Pharma, Corium and a long tail of generic atomoxetine and guanfacine makers. Qelbree's differentiation is that it is non-stimulant and not a controlled substance, but the category is price-competitive and generic stimulant supply has largely normalized. Multiple ANDA filers are already challenging Qelbree's patents.
Parkinson's disease therapies
AbbVie is the direct competitor to ONAPGO with VYALEV, a continuous subcutaneous levodopa-carbidopa infusion approved months before ONAPGO, and also sells DUOPA. Amneal (CREXONT), Bausch Health and generic amantadine makers compete with GOCOVRI. Analysts have described VYALEV and ONAPGO as broadly comparable on efficacy, so prescriber preference, tolerability and payer coverage decide share.
Mid-cap CNS specialty pharma peers
Axsome Therapeutics, Harmony Biosciences, Alkermes, Neurocrine Biosciences and Jazz Pharmaceuticals compete for the same neurologist and psychiatrist call points, the same in-licensing and acquisition targets, and the same investor capital. Indivior, the merger partner, sits in this group as well with its opioid-use-disorder franchise.
What stocks are similar to Supernus Pharmaceuticals, Inc. (SUPN)?
Other names that sit close to SUPN: same theme, named as a direct competitor, or held beside it in the same funds. Each entry says which. Worth a look if you are thinking about diversification within a thesis rather than concentration on one ticker.
How to invest in Supernus Pharmaceuticals, Inc. (SUPN)
There are three common ways to get SUPN exposure. Buy shares (or fractional shares) directly at any major broker. Hold an ETF that includes it, which spreads the position across many companies. Or build it into a focused thematic portfolio, so SUPN sits alongside other stocks that express the same thesis.
Walnut takes the portfolio route. Describe a thesis where SUPN fits (for example “AI infrastructure” or “dividend-growth large-caps”) and the AI proposes 5 to 6 constituents with target weights. You review the plan and fund it through your own broker when you're ready.
New to this? Start with how to invest in stocks, see how to analyze a stock with AI, or compare the best AI stock analyzers.
The bottom line on Supernus Pharmaceuticals, Inc. (SUPN)
More on Supernus Pharmaceuticals, Inc. (SUPN)
Whether SUPN is worth buying today depends more on your time horizon and what you already hold than on any single call. We walk through valuation, what would have to go right, and the risks in is SUPN a buy or a sell?, and where the stock could go from here in the SUPN stock forecast.
For income investors, whether SUPN pays a dividend and how the payout looks is covered in does SUPN pay a dividend? And to weigh SUPN against a peer, read the full side-by-side comparisons: SUPN vs ABBV and SUPN vs AMRX.
Wondering how SUPN fits the portfolio you already own? Walnut is an AI investing app that connects your brokerage read-only and answers questions like that about your actual holdings: overlap, concentration, and how each position tracks the S&P 500. Compare the best AI portfolio analyzers or see the best AI investing apps in 2026.
Investing in Supernus Pharmaceuticals, Inc. with AI
Connect the broker you already use and ask Walnut's AI how SUPN fits what you actually hold: whether you own it already through a fund, what it would do to your concentration, and how it has tracked the S&P 500. Read-only by default, and you approve anything before it reaches your broker.
FAQ
What does Supernus Pharmaceuticals actually sell?
+
Prescription central nervous system medicines. The four growth products are Qelbree (non-stimulant ADHD), GOCOVRI (Parkinson's dyskinesia), ONAPGO (continuous apomorphine infusion for advancing Parkinson's) and ZURZUVAE (oral postpartum depression treatment, revenue split with Biogen). Older products include Trokendi XR and Oxtellar XR for epilepsy, plus APOKYN, MYOBLOC and XADAGO.
Why did Supernus report a loss if revenue grew 32%?
+
The second-quarter 2026 net loss of ~$58 million was driven by a ~$55 million non-cash impairment of the APOKYN intangible asset, on top of ~$25 million of quarterly amortization from prior acquisitions. Adjusted operating earnings for the same quarter were ~$31 million. Management's full-year GAAP guidance still calls for an operating loss of ~$20 million to ~$50 million.
Is Qelbree protected from generic competition?
+
Its new-chemical-entity exclusivity expired in April 2026. Six US patents run from September 2029 to April 2035, but Supernus received Paragraph IV notices from generic filers starting in May 2025 and is litigating against multiple ANDA applicants. The outcome of that litigation, not the nominal patent dates, determines when generics can enter.
How fast is the legacy business declining?
+
Quickly. In the second quarter of 2026 Trokendi XR fell ~25% to ~$8 million, Oxtellar XR fell ~25% to ~$9 million, APOKYN fell ~51% to ~$6 million, and other older products fell ~71%. Combined Trokendi and Oxtellar guidance for the full year is only ~$50 million to ~$60 million, against a total company target of ~$860 million to ~$890 million.
Does Supernus pay a dividend?
+
No. Supernus has not paid a dividend and cash has gone toward acquisitions (Sage Therapeutics in 2025), the ONAPGO launch and the pipeline. Note that in the merger structure it is Indivior shareholders, not Supernus shareholders, who receive the ~$1 billion pre-closing special cash dividend.
What is in the pipeline?
+
SPN-817 is in Phase 2b for treatment-resistant focal seizures with roughly 258 patients enrolled, SPN-820 is in a Phase 2b trial in about 200 adults with major depressive disorder, and SPN-443 was expected to start Phase 1 in ADHD in the second half of 2026. An earlier SPN-820 study in treatment-resistant depression missed its primary endpoint in February 2025, which is a reminder of the base rate here.
What are the main things that could go wrong?
+
Qelbree growth slowing or losing a patent case, ONAPGO's single-source manufacturing interrupting supply again before a second supplier is approved, AbbVie's VYALEV taking share in device-delivered Parkinson's care, the merger failing to close or failing to deliver the ~$125 million in targeted synergies, and the added leverage from the ~$650 million term loan funding the pre-closing dividend. There is also an APOKYN antitrust suit pending in Delaware and routine merger-objection investigations by shareholder law firms.
Walnut is informational, not investment advice. Financial figures on this page are approximations; always verify current numbers with Supernus Pharmaceuticals, Inc.'s investor relations page or your broker before making investment decisions.