Travere Therapeutics, Inc. (TVTX) Stock Price & How to Invest

Last updated October 2026

Short answer

TVTX is Travere Therapeutics, a San Diego rare-disease biopharma whose value rests almost entirely on one drug, FILSPARI, now approved in both IgA nephropathy and FSGS. Owning it is a bet that a single kidney franchise can scale toward management's stated $3B-plus peak ambition faster than a crowded field of newer competitors can take share. A CEO change is also under way: Eric Dube steps down on December 1, 2026, handing over to Bradley Campbell, the former chief executive of Amicus Therapeutics. The shares closed near $50 on October 16, 2026, up about 27% year to date but about 20% below where they stood a month earlier.

TVTX stock price

As of 2026-11-04, Travere Therapeutics, Inc. (TVTX) last closed at $52.42, up 55.5% over the past year. Over the past 52 weeks it has traded between $26.79 and $67.52.

TVTX last close
$52.42
1 day
+6.09%
1 month
-9.10%
1 year
+55.46%
52-week range
$26.79 to $67.52
Last close
2026-11-04

Prices are daily closing prices from Yahoo Finance and may be delayed. For the live quote, check your broker or Travere Therapeutics, Inc.'s investor relations page. Walnut is informational, not investment advice.

What does Travere Therapeutics, Inc. (TVTX) do?

Travere Therapeutics (Nasdaq: TVTX) develops and sells treatments for rare kidney and metabolic diseases. Its lead product, FILSPARI (sparsentan), is a once-daily oral dual endothelin and angiotensin receptor antagonist that received full FDA approval for IgA nephropathy in September 2024 and, in April 2026, became the first FDA-approved therapy specifically for focal segmental glomerulosclerosis (FSGS). The company also sells THIOLA and THIOLA EC (tiopronin) for cystinuria, a small but steady legacy franchise, and partners FILSPARI outside the US with CSL Vifor in Europe and Everest Medicines in parts of Asia. Behind the commercial business sits a nephrology and metabolic pipeline led by pegtibatinase for classical homocystinuria and the in-licensed BTK inhibitor civorebrutinib for immune-mediated kidney diseases including primary membranous nephropathy.

The investment picture is unusually concentrated. In the second quarter of 2026 Travere reported total revenue of ~$169.6 million, of which FILSPARI US net sales were ~$141.1 million, up ~96% year over year, on 2,012 new patient start forms across both indications. Gross margin runs above 98%, so essentially every incremental sales dollar flows toward covering an operating base of roughly $60 million of quarterly R&D and $96 million of SG&A. Total revenue grew about 48% year over year, though earnings per share of about -$0.10 came in below what analysts had expected. The company is not yet GAAP profitable (a ~$34.8 million net loss in the quarter and about $68 million over the trailing twelve months), but operating cash flow is positive at roughly $93 million over the trailing year, and cash plus marketable securities stood at ~$489 million against ~$617 million of mostly convertible debt.

Several things have happened since. On September 21, 2026 Travere announced that Eric Dube will step down as president and CEO to focus on his health and family, with Bradley L. Campbell, who spent nearly 20 years at Amicus Therapeutics and ran it from 2022 until its sale to BioMarin, taking over on December 1, 2026; Dube stays on as an executive advisor through February 15, 2027. Two days later the company received a US patent notice of allowance covering methods of using FILSPARI in FSGS, and in October it said it would present new FILSPARI data in IgAN and FSGS at ASN Kidney Week 2026. Insiders sold shares in September, including one sale of about $25.4 million. The stock closed near $50.19 on October 16, 2026, up about 27% year to date and 82% over one year but down about 20% over the past month, for a market value near $4.7 billion. Third-quarter results are expected around October 29, 2026, with consensus near $196 million of revenue. What an owner is really underwriting is durability: whether FILSPARI's dual-mechanism label and first-mover FSGS position hold up against Novartis, Otsuka and Vera Therapeutics, all of whom now have approved IgAN drugs of their own.

What's driving Travere Therapeutics, Inc. (TVTX)?

1. The FSGS launch, a market with no prior approved therapy

FSGS is the second indication and the cleaner competitive setup, because until April 2026 no drug was approved for it at all. Q2 2026 was the first full quarter with FILSPARI available in both indications, and management noted that roughly 70% of early FSGS prescribers already had IgAN experience with the brand while about 30% were new to it. That mix matters: the existing nephrology salesforce is doing double duty, which is why revenue grew faster than commercial spend.

2. Compounding the IgA nephropathy base

IgAN remains the larger revenue pool today and is where FILSPARI built its patient base after full approval in 2024. Growth here now depends on treating earlier in the disease course and on retention rather than on being the only option. Management has repeatedly pointed to a more than $3 billion peak annual sales ambition for the franchise, a figure that only works if both indications scale together.

3. Operating leverage from a ~98% gross margin

Travere's cost of goods is nearly nothing, so the path from a ~$43 million trailing net loss to sustained profitability is arithmetic on top-line growth rather than a manufacturing or pricing project. Trailing operating cash flow is already positive at roughly $93 million, and analysts on average expect revenue of about $725 million in 2026 and about $1.08 billion in 2027, with EPS rising to about $5.64 in 2027. The offsetting force is that both R&D and SG&A stepped up in 2026 to fund the FSGS launch and the pegtibatinase Phase 3.

4. Pipeline optionality beyond the single product

Pegtibatinase for classical homocystinuria is in the Phase 3 HARMONY study with topline data anticipated in the second half of 2027, and civorebrutinib was in-licensed to extend the company into other immune-mediated kidney diseases. Neither contributes revenue today. Their function in the story is to give Travere a second act if FILSPARI's growth curve flattens sooner than the peak-sales ambition implies.

5. Leadership handover and patent protection

Bradley Campbell takes over as CEO on December 1, 2026. His record at Amicus, where the company grew from a single product into a multi-franchise rare-disease business before BioMarin bought it, maps closely onto what Travere needs to do next. Separately, the September 2026 notice of allowance for a US patent on methods of using FILSPARI in FSGS is aimed at extending the exclusivity runway for the newer indication. Both matter for durability, the question that sits under the whole valuation.

What are the risks to Travere Therapeutics, Inc. (TVTX)?

Single-product concentration is the defining risk: FILSPARI is the overwhelming majority of revenue, so any safety signal, label change, reimbursement setback or competitive loss hits the whole company rather than one segment. The IgA nephropathy field got crowded quickly, with Novartis marketing both VANRAFIA (atrasentan) and FABHALTA (iptacopan), Otsuka selling TARPEYO and Voyxact, and Vera Therapeutics winning approval for Trutakna (atacicept), and FILSPARI carries a REMS program and a boxed warning for hepatotoxicity and embryo-fetal toxicity that at least one rival endothelin blocker does not. Regulatory timing has already proven volatile for this stock: shares fell more than 30% in January 2026 when the FDA extended the FSGS review, and several plaintiff law firms opened securities investigations afterward, though the application was subsequently approved. The balance sheet carries more debt (~$617 million, largely convertible) than cash (~$489 million), so continued losses would eventually mean dilution or refinancing. A CEO transition in the middle of a two-indication launch adds execution risk, and the stock fell about 20% in the month to mid-October 2026 as insiders sold shares and the new FILSPARI data drew a muted reaction. Finally, pegtibatinase data is more than a year out, which leaves little to cushion a disappointment in the commercial franchise before then.

What is the Travere Therapeutics, Inc. (TVTX) forecast?

14 analysts publish price targets on TVTX, averaging $75.21 against a $49.16 price as of November 2026, or +53.0%. The published targets run from $62.00 to $90.00, a moderate spread, and the ratings split 14 buy, 1 hold, 0 sell. Over the last six months there have been 10 raises and 0 cuts among the published actions. A price target is what an analyst published on a date, not a prediction, and sell-side ratings skew positive across the whole market.

Read the full TVTX forecast and price target for the target table, the recent rating actions by firm, and how the consensus has shifted.

Is TVTX a buy or a sell?

We give no verdict on Travere Therapeutics, Inc.. Both cases are real, which is why the question is contested at all, so here is the strongest version of each.

The case for buying. The FSGS launch, a market with no prior approved therapy. FSGS is the second indication and the cleaner competitive setup, because until April 2026 no drug was approved for it at all. The most optimistic published target, $90.00, assumes this works close to its best case.

The case against. Single-product concentration is the defining risk: FILSPARI is the overwhelming majority of revenue, so any safety signal, label change, reimbursement setback or competitive loss hits the whole company rather than one segment. The most pessimistic target, $62.00, is roughly what TVTX is worth if this bites instead.

Read the full bull and bear case on TVTX, including what would have to change to break either one. Walnut is not an investment adviser.

Has Travere Therapeutics, Inc. (TVTX) split its stock?

No. Travere Therapeutics, Inc. (TVTX) has not split its stock in the last 10 years. That is a statement about the window we check rather than about the company’s entire history, so an older split is possible. It also matters less than it once did: fractional shares mean a high price per share no longer keeps smaller investors out, which removed most of the practical reason to split.

How is Travere Therapeutics, Inc. (TVTX) valued? (approximate, October 2026)

A simple financial snapshot. These are approximations and refresh quarterly; for current figures see Travere Therapeutics, Inc.'s investor relations page or your broker.

  • Revenue (TTM): ~$591M; Q2 2026 total revenue up ~48% year over year
  • Q2 2026 revenue: ~$169.6M total, with FILSPARI US net sales of ~$141.1M (+96% YoY)
  • Net income (TTM): ~-$68M net loss (~$0.74 loss per share); Q2 GAAP loss ~$34.8M
  • Operating cash flow (TTM): ~$93M
  • Cash and debt: ~$489M cash and marketable securities vs ~$617M total debt (net debt ~$128M)
  • Market cap: ~$4.7B, roughly 7.9x trailing sales, at ~$50 a share
  • Forward P/E (2027 consensus EPS): ~9x

There is no meaningful trailing P/E here because Travere is still running a small net loss, so the market is valuing it on the revenue trajectory and on how close FILSPARI gets to the stated $3B-plus peak ambition; on analysts' 2027 EPS estimate of about $5.64 the forward multiple is near 9. The stock has moved violently in both directions over the past year, with a 52-week range of roughly $22.59 to $68.73, which tells you how much of the price is regulatory and launch expectation rather than trailing results. At about 7.9x sales with revenue still growing near 50%, the multiple is not extreme for a growth biotech but it does assume the launch curve holds.

Who competes with Travere Therapeutics, Inc. (TVTX)?

Approved IgA nephropathy rivals

Novartis is the most direct threat, selling both VANRAFIA (atrasentan), an endothelin A receptor blocker that competes on mechanism without a REMS requirement, and FABHALTA (iptacopan), an oral Factor B complement inhibitor. Otsuka markets TARPEYO (targeted-release budesonide) and Voyxact (sibeprenlimab), and Vera Therapeutics won FDA approval for Trutakna (atacicept). Because these drugs hit different points in the disease pathway, the competition is partly about combination sequencing rather than pure head-to-head substitution, but they all compete for the same nephrologist's prescription pad.

Background standard of care

Before any branded rare-kidney therapy, patients are typically on generic RAS blockade (ACE inhibitors or ARBs) and increasingly on SGLT2 inhibitors such as AstraZeneca's Farxiga or Boehringer Ingelheim and Eli Lilly's Jardiance, which have their own chronic kidney disease data. These are cheap, familiar and additive rather than displaced, so they set the bar FILSPARI has to clear on proteinuria reduction and eGFR preservation to justify its price.

Other rare-disease and nephrology biotechs

Companies such as Vertex Pharmaceuticals, Alnylam, Apellis and BioCryst compete less on the same prescription and more on the same scarce inputs: nephrology trial sites, rare-disease patient identification, in-licensing deals for assets like civorebrutinib, and the pool of investor capital willing to fund pre-profit rare-disease franchises. Travere's pegtibatinase program for homocystinuria sits squarely in this category of contested rare metabolic markets.

What stocks are similar to Travere Therapeutics, Inc. (TVTX)?

Other names that sit close to TVTX: same theme, named as a direct competitor, or held beside it in the same funds. Each entry says which. Worth a look if you are thinking about diversification within a thesis rather than concentration on one ticker.

How to invest in Travere Therapeutics, Inc. (TVTX)

There are three common ways to get TVTX exposure. Buy shares (or fractional shares) directly at any major broker. Hold an ETF that includes it, which spreads the position across many companies. Or build it into a focused thematic portfolio, so TVTX sits alongside other stocks that express the same thesis.

Walnut takes the portfolio route. Describe a thesis where TVTX fits (for example “AI infrastructure” or “dividend-growth large-caps”) and the AI proposes 5 to 6 constituents with target weights. You review the plan and fund it through your own broker when you're ready.

New to this? Start with how to invest in stocks, see how to analyze a stock with AI, or compare the best AI stock analyzers.

The bottom line on Travere Therapeutics, Inc. (TVTX)

Travere is a one-product commercial story with real, fast-growing revenue and a differentiated label, priced at roughly eight times trailing sales on the assumption that the FSGS launch keeps compounding, with a new CEO taking over in December 2026.

More on Travere Therapeutics, Inc. (TVTX)

Whether TVTX is worth buying today depends more on your time horizon and what you already hold than on any single call. We walk through valuation, what would have to go right, and the risks in is TVTX a buy or a sell?, and where the stock could go from here in the TVTX stock forecast.

For income investors, whether TVTX pays a dividend and how the payout looks is covered in does TVTX pay a dividend? And to weigh TVTX against a peer, read the full side-by-side comparisons: TVTX vs NVS and TVTX vs VERA.

Wondering how TVTX fits the portfolio you already own? Walnut is an AI investing app that connects your brokerage read-only and answers questions like that about your actual holdings: overlap, concentration, and how each position tracks the S&P 500. Compare the best AI portfolio analyzers or see the best AI investing apps in 2026.

Investing in Travere Therapeutics, Inc. with AI

Connect the broker you already use and ask Walnut's AI how TVTX fits what you actually hold: whether you own it already through a fund, what it would do to your concentration, and how it has tracked the S&P 500. Read-only by default, and you approve anything before it reaches your broker.

FAQ

What does Travere Therapeutics actually do?

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Travere is a commercial-stage biopharmaceutical company focused on rare kidney and metabolic diseases. It sells FILSPARI (sparsentan) for IgA nephropathy and focal segmental glomerulosclerosis, and THIOLA and THIOLA EC (tiopronin) for cystinuria. It also runs a clinical pipeline led by pegtibatinase for classical homocystinuria.

How much of Travere's revenue comes from FILSPARI?

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The overwhelming majority. In Q2 2026, FILSPARI US net sales were ~$141.1 million out of ~$169.6 million in total revenue, or roughly 83%. That share has been rising as FILSPARI grows and the legacy THIOLA franchise stays flat, which makes TVTX effectively a single-product story.

Is Travere Therapeutics profitable?

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Not yet on a GAAP basis. Trailing twelve-month net income was about -$68 million, and Q2 2026 showed a ~$34.8 million net loss (~$9.0 million on a non-GAAP adjusted basis). Operating cash flow over the trailing year was positive at roughly $93 million, and analysts expect the company to report a profit for full-year 2026.

Why did TVTX stock fall so sharply in January 2026?

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Shares dropped more than 30% intraday on January 13, 2026 after the FDA extended its review of the FILSPARI supplemental application in FSGS, treating additional company submissions as a major amendment and pushing the target action date to April 13, 2026. Several plaintiff law firms opened securities investigations afterward. The FDA subsequently approved the FSGS indication.

What is FSGS and why does that approval matter?

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Focal segmental glomerulosclerosis is a rare disease that scars the kidney's filtering units and often progresses to kidney failure. No therapy had ever been specifically approved for it in the US, so FILSPARI's April 2026 approval opened a market with no branded incumbent, which is a materially cleaner competitive setup than IgA nephropathy.

Who competes with FILSPARI?

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In IgA nephropathy, Novartis sells VANRAFIA (atrasentan) and FABHALTA (iptacopan), Otsuka sells TARPEYO and Voyxact, and Vera Therapeutics has Trutakna (atacicept). Underneath all of them, generic RAS blockers and SGLT2 inhibitors remain the background standard of care that any new drug is layered on top of.

How is TVTX valued relative to its revenue?

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At a ~$4.7 billion market cap against ~$591 million in trailing revenue, TVTX trades at roughly 7.9 times sales as of mid-October 2026, and near 9 times analysts' 2027 earnings estimate. There is no meaningful trailing P/E because the company still posts a small net loss, so the valuation reflects expected growth toward management's stated $3 billion-plus peak sales ambition rather than current earnings.

What would change the picture for Travere from here?

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The near-term variables are the third-quarter report expected around October 29, 2026, the handover to new CEO Bradley Campbell on December 1, 2026, the pace of FSGS patient starts, whether IgA nephropathy share holds as newer mechanisms launch, and how quickly the ~98% gross margin converts revenue growth into sustained profitability. Further out, Phase 3 topline data for pegtibatinase in homocystinuria is anticipated in the second half of 2027 and is the main event that could make TVTX something other than a one-product company.

Who is Travere's new CEO?

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Bradley L. Campbell becomes president and CEO on December 1, 2026, succeeding Eric Dube, who is stepping down to focus on his health and family and will remain an executive advisor through February 15, 2027. Campbell spent nearly 20 years at Amicus Therapeutics, becoming CEO in 2022, and earlier held commercial and business development roles at Genzyme and Bristol-Myers Squibb. He also joins Travere's board.

How has TVTX stock performed in 2026?

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As of October 16, 2026, TVTX closed near $50.19, up about 27% year to date and about 82% over the past year, within a 52-week range of roughly $22.59 to $68.73. The shares fell about 20% over the past month, a period that included the CEO transition announcement and insider sales. The average analyst target is about $75 across 14 analysts. Walnut is not an investment adviser, so this is descriptive, not advice.

Walnut is informational, not investment advice. Financial figures on this page are approximations; always verify current numbers with Travere Therapeutics, Inc.'s investor relations page or your broker before making investment decisions.