ABT vs TMO: Which Is the Better Buy in 2026?

Last updated October 2026

Short answer

TMO is the larger of the two ($255.13B market cap): the incumbent the market prices for continued execution (25.02x forward earnings, beta 0.88). ABT is the smaller challenger ($182.70B), cheaper on forward earnings (17.29x): more room to run, but more to prove. The real question is which set of drivers you believe, and whether owning one (or both) leaves you over-concentrated.

ABT vs TMO: the tie-breaker metrics

Same yardstick, side by side (as of October 2026). Valuation lined up like this is most meaningful for two names in the same corner of the market, which these are. Figures are approximate; verify before investing.

MetricABTTMOWhat it tells you
Market cap$182.70B$255.13BSize. The larger name is the incumbent; the smaller has more room to grow and more to prove.
Forward P/E17.2925.02Valuation on next year's expected earnings, the same yardstick for both. Lower is cheaper for that growth; higher means the market is paying up.
Trailing P/E33.8437.14Valuation on the last 12 months. A big drop from trailing to forward means the market expects earnings to jump, so more growth is already in the price.
Beta0.580.88Volatility vs the market. Above 1 swings harder than the index; below 1 is steadier. Higher beta means bigger drawdowns to hold through.
Price vs 52-week range46% of range95% of rangeWhere today's price sits between the 52-week low and high. Near the high is momentum with less margin of safety; near the low is out of favor or a discount, depending on why.
Price / book3.554.84How much you pay over book value. Very high can signal an asset-light, high-return business or a rich price.

Reading it: ABT is the cheaper of the two on forward earnings, but cheaper is not the same as better. Pair the valuation with growth (how far the forward P/E sits below the trailing P/E) and risk (beta) before you decide.

Before you buy: how ABT and TMO affect your concentration

The metrics above tell you which is the marginally better business. The bigger risk for most people is not picking the slightly worse stock, it is over-concentrating. ABT and TMO share themes, so owning both, or adding either to what you already hold, can quietly push a large share of your portfolio into one bet.

This is the part a generic comparison page cannot answer, because it depends on what you own. Connect your brokerage and Walnut shows your real, combined ABT and TMO exposure, flags overlap with your existing positions, and tells you if adding one would tip you past a concentration you are comfortable with, read-only by default, with your login staying at your broker. Walnut is not an investment adviser.

What does Abbott Laboratories (ABT) do?

Abbott Laboratories is a global healthcare company headquartered in North Chicago, Illinois, that discovers, develops, manufactures, and sells health care products in more than 160 countries through four segments: Medical Devices, Diagnostic Products, Nutritional Products, and Established Pharmaceutical Products. Medical Devices, the largest segment at roughly $21.4 billion in 2025 revenue, includes the FreeStyle Libre family of continuous glucose monitors, structural heart products (Navitor, TriClip), electrophysiology systems (AVEIR leadless pacemaker, Volt pulsed field ablation, TactiFlex Duo), vascular devices, and heart-failure technologies (CardioMEMS). Diagnostics contributed roughly $8.9 billion in 2025 before the Exact Sciences deal, Nutrition roughly $8.5 billion (anchored by Similac infant formula and Ensure adult nutrition), and Established Pharmaceuticals roughly $5.5 billion in branded generics sold primarily in emerging markets.

Full ABT guide

What does Thermo Fisher Scientific (TMO) do?

Thermo Fisher Scientific, headquartered in Waltham, Massachusetts, is a global provider of scientific instruments, consumables, reagents, and services used across pharmaceutical and biotech drug development, clinical diagnostics, academic research, and environmental and industrial testing. The company operates through four reportable segments: Life Sciences Solutions (reagents, proteins, and consumables for research and bioproduction), Analytical Instruments (mass spectrometers, chromatography systems, electron microscopes, and laboratory equipment), Specialty Diagnostics (clinical diagnostic kits and transplant diagnostics), and Laboratory Products and Biopharma Services (supply-chain distribution, contract research through PPD, and contract drug manufacturing through Patheon). Revenue is generated through instrument sales, high-margin consumables and reagents that customers repurchase continuously, long-term service contracts, and growing contract development and manufacturing (CDMO) fees; consumables and services collectively account for a majority of annual sales and provide durable recurring revenue.

Full TMO guide

ABT vs TMO: how do they differ?

Both fit overlapping themes, but they are not interchangeable. The useful comparison is which set of drivers and risks you want exposure to.

  • ABT drivers: FreeStyle Libre: A Platform, Not Just a Product; Cardiovascular and Electrophysiology Momentum.
  • TMO drivers: Bioprocessing and Biologic Drug Manufacturing Tailwind; Recurring Consumables and Reagents Engine.

Which fits which kind of investor

A faster-growing, richer-valued name usually swings harder, so it suits a longer horizon and a higher tolerance for volatility; a steadier, more cash-generative business suits a more conservative or income-minded investor. The honest test is which set of risks you could hold through a drawdown: The most acute near-term risk is infant formula litigation: juries have delivered verdicts including a $53 million compensatory award in late March 2026 and a separately upheld $495 million verdict, with hundreds of additional NEC-related cases pending, and a securities class action filed in 2026 adds a parallel legal exposure track targeting alleged investor misstatements. For TMO, the most significant near-term risk is a contraction in research funding from government agencies (including NIH) and from biotech companies whose access to capital markets has historically been cyclical; when funding tightens, customers delay instrument purchases and reduce consumable orders, pressuring organic revenue growth.

ABT or TMO: which should you pick?

Growth-minded investors who believe the theme has years to run tend to accept the richer multiple for more upside; value-minded investors lean toward the cheaper forward earnings and steadier profile. Pick ABT if you believe its drivers more; TMO if you believe its. Many investors hold both, but since they share themes, that is a concentrated bet, not diversification. Decide deliberately and check overlap. For the full detail, see the ABT and TMO guides.

ABT vs TMO: the full fundamentals

ABT. ABT's trailing GAAP P/E of about 34x is inflated by acquisition amortization and one-time costs from the Exact Sciences deal; on forward earnings the stock trades near 17x, well below its own 5-year and 10-year historical averages, after a roughly 16% decline in 2026. Revenue growth has remained positive, and the raised adjusted EPS guidance of $5.45-$5.60 implies a forward adjusted P/E of about 19x at the October 16 price of $104.44, below the average analyst target of about $121. Q3 2026 results are due October 21, with company guidance of $1.38-$1.46 adjusted EPS and consensus near $1.41 on about $13.0 billion of sales.

TMO. Thermo Fisher's multiple has expanded sharply since mid-2026 as organic growth re-accelerated: the stock trades at roughly 25 times forward earnings and ~37 times trailing GAAP earnings, which include heavy acquisition amortization. Analysts expect 2026 adjusted EPS of ~$25.14 on ~$47.9 billion of revenue, and ~$27.58 on ~$50.4 billion in 2027, both roughly 10% growth. The October 21 third-quarter report will test whether the second quarter's 5% organic growth holds; free cash flow of roughly $6.3 billion in 2025 still gives the company flexibility for repurchases, dividends and acquisitions.

Headline figures (approximate, October 2026): ABT shows revenue (ttm) ~$46.6 billion (Q2 2026 sales $12.59 billion, +13% reported, +4.8% comparable), revenue (fy 2025) ~$44.3 billion (+5.7% YoY), net income (ttm) ~$5.4 billion (GAAP EPS ~$3.10), net profit margin (ttm) ~11.7%; TMO shows revenue (ttm) ~$46.3 billion; full year 2025 ~$44.6 billion, q2 2026 revenue ~$11.99 billion, up 10% reported and 5% organic, q2 2026 adjusted eps ~$6.03 (+13%) vs ~$5.71 expected, margins (ttm) Gross ~41%, GAAP operating ~19%, net ~15%.

The bottom line: ABT vs TMO

ABT and TMO are related but distinct: same themes, different businesses and risks. Neither wins in the abstract; the right pick is whichever thesis you actually believe, sized so you are not over-concentrated in one theme. Walnut can show your combined ABT and TMO exposure against your real portfolio. It is not an investment adviser.

Wondering how ABT or TMO fits the portfolio you already own? Walnut is an AI investing app that connects your brokerage read-only and answers questions like that about your actual holdings: overlap, concentration, and how each position tracks the S&P 500. Compare the best AI portfolio analyzers or see the best AI investing apps in 2026.

Investing in Abbott Laboratories with AI

Connect the broker you already use and ask Walnut's AI how ABT fits what you actually hold: whether you own it already through a fund, what it would do to your concentration, and how it has tracked the S&P 500. Read-only by default, and you approve anything before it reaches your broker.

FAQ

What is the difference between ABT and TMO?

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Abbott Laboratories is a global healthcare company headquartered in North Chicago, Illinois, that discovers, develops, manufactures, and sells health care products in more than 160 countries through four segments: Medical Devices, Diagnostic Products, Nutritional Products, and Established Pharmaceutical Products. Thermo Fisher Scientific, headquartered in Waltham, Massachusetts, is a global provider of scientific instruments, consumables, reagents, and services used across pharmaceutical and biotech drug development, clinical diagnostics, academic research, and environmental and industrial testing. They show up together because they share investment themes, but they are different businesses, so the better fit depends on which thesis you are expressing.

Is ABT or TMO the better stock?

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Neither is universally better. TMO is the larger incumbent; ABT is the smaller challenger and looks cheaper on forward earnings. Walnut is informational, not investment advice. Compare what each does, the tie-breaker metrics above, and the risks, then decide which fits your thesis and what you already own.

Which is cheaper, ABT or TMO?

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On forward P/E (as of October 2026), ABT trades at 17.29x and TMO at 25.02x, so ABT is the cheaper of the two on next year's expected earnings. A lower multiple is not automatically the better buy: a richer valuation can be justified by faster growth, and a lower one can reflect real risk. Weigh the multiple against how fast each business is compounding.

Should you own both ABT and TMO?

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Because they share themes, owning both concentrates you in that theme. That can be intentional (a focused bet) or accidental (less diversification than it looks). Walnut can show your combined exposure across both, and whether adding either over-concentrates you, before you buy.

What are the risks of ABT vs TMO?

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ABT: The most acute near-term risk is infant formula litigation: juries have delivered verdicts including a $53 million compensatory award in late March 2026 and a separately upheld $495 million verdict, with hundreds of additional NEC-related cases pending, and a securities class action filed in 2026 adds a parallel legal exposure track targeting alleged investor misstatements. Abbott has started to narrow this exposure, reaching agreements in August 2026 to resolve a portion of the preterm-formula litigation and an agreement with the Department of Justice in September 2026 on claims tied to the 2022 recall, but the remaining liability is still open-ended. Integration of the approximately $21 billion Exact Sciences acquisition introduces execution risk, amortization and elevated SGA costs: GAAP EPS was only $0.53 in Q2 2026 against adjusted EPS of $1.31, and the trailing GAAP P/E is about 34x even though the forward multiple is about 17x. Organic growth also slowed to 4.8% in Q2 2026 on a comparable basis, below the full-year 6.5-7.5% guide. Foreign exchange swings move reported international revenue by several percentage points, and any meaningful dollar strengthening would pressure reported results disproportionately given Abbott's broad non-US exposure. Competitive disruption in continuous glucose monitoring from DexCom and emerging players, along with pricing pressure from government payers and the Inflation Reduction Act, represent structural long-term headwinds. TMO: The most significant near-term risk is a contraction in research funding from government agencies (including NIH) and from biotech companies whose access to capital markets has historically been cyclical; when funding tightens, customers delay instrument purchases and reduce consumable orders, pressuring organic revenue growth. Thermo Fisher's active acquisition strategy carries integration and leverage risk, particularly after committing approximately $13 billion to mergers and acquisitions in 2025 alone; total debt stood near ~$42.6 billion against ~$4.1 billion of cash on the latest balance sheet, and a large deal that underperforms expectations could weigh on earnings and the balance sheet simultaneously. Geopolitical friction, particularly regarding China, creates both a demand risk (softer orders from Chinese academic and industrial customers) and a supply chain risk, while tariff policy changes can disrupt cost structures. Finally, valuation risk has grown: after a ~31% rally in three months the stock trades near ~37 times trailing GAAP earnings and ~25 times forward estimates, essentially at the ~$689 average analyst target, which leaves less room for disappointment if organic growth slips back from the second quarter's 5%.

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Walnut is informational, not investment advice. This page is descriptive and not a recommendation to buy or sell ABT or TMO; figures are approximate and dated (as of October 2026). Verify current data before investing.