ABT vs MRK: How Abbott Laboratories and MRK Compare (2026)

Same yardstick, side by side (as of July 2026). Valuation lined up like this is most meaningful for two names in the same corner of the market, which these are. Figures are approximate; verify before investing.

Reading it: MRK is the cheaper of the two on forward earnings, but cheaper is not the same as better. Pair the valuation with growth (how far the forward P/E sits below the trailing P/E) and risk (beta) before you decide.

The metrics above tell you which is the marginally better business. The bigger risk for most people is not picking the slightly worse stock, it is over-concentrating. ABT and MRK share themes, so owning both, or adding either to what you already hold, can quietly push a large share of your portfolio into one bet.

This is the part a generic comparison page cannot answer, because it depends on what you own. Connect your brokerage and Walnut shows your real, combined ABT and MRK exposure, flags overlap with your existing positions, and tells you if adding one would tip you past a concentration you are comfortable with, read-only by default, with your login staying at your broker. Walnut is not an investment adviser.

Abbott Laboratories is a global healthcare company headquartered in North Chicago, Illinois, that discovers, develops, manufactures, and sells health care products in more than 160 countries through four segments: Medical Devices, Diagnostic Products, Nutritional Products, and Established Pharmaceutical Products. Medical Devices, the largest segment at roughly $21.4 billion in 2025 revenue, includes the FreeStyle Libre family of continuous glucose monitors, structural heart products (Navitor, TriClip), electrophysiology systems (AVEIR leadless pacemaker), vascular devices, and heart-failure technologies. Diagnostics contributes roughly $8.9 billion, Nutrition roughly $8.5 billion (anchored by Similac infant formula and Ensure adult nutrition), and Established Pharmaceuticals roughly $5.5 billion in branded generics sold primarily in emerging markets.

Full ABT guide

Merck and Co., Inc. (NYSE: MRK) is a global research-intensive biopharmaceutical company headquartered in Rahway, New Jersey. It discovers, develops, manufactures, and markets prescription medicines, vaccines, and biologic therapies across oncology, infectious disease, cardiovascular, and diabetes, alongside a substantial Animal Health segment that sells vaccines and medicines for livestock and companion animals. The company operates under the MSD name outside the United States and Canada. Revenue flows primarily from pharmaceutical product sales, with oncology representing more than 60 percent of pharmaceutical revenue. Keytruda, a PD-1 inhibitor approved in more than 40 cancer indications, is the world's best-selling drug and the dominant revenue driver. Other meaningful contributors include the Gardasil HPV vaccine franchise, pulmonary arterial hypertension therapy Winrevair, pneumococcal vaccine Capvaxive, antiviral Lagevrio, and the Animal Health portfolio led by the Bravecto parasite treatment and Allflex livestock intelligence products.

Full MRK guide

Both fit overlapping themes, but they are not interchangeable. The useful comparison is which set of drivers and risks you want exposure to.

• ABT drivers: FreeStyle Libre: A Platform, Not Just a Product; Cardiovascular and Electrophysiology Momentum.
• MRK drivers: Keytruda's remaining runway is substantial; A tripling of the Phase III pipeline provides post-cliff optionality.

A faster-growing, richer-valued name usually swings harder, so it suits a longer horizon and a higher tolerance for volatility; a steadier, more cash-generative business suits a more conservative or income-minded investor. The honest test is which set of risks you could hold through a drawdown: The most acute near-term risk is infant formula litigation: juries have delivered verdicts including a $53 million compensatory award in late March 2026 and a separately upheld $495 million verdict, with hundreds of additional NEC-related cases still pending, and a securities class action filed in 2026 adds a parallel legal exposure track targeting alleged investor misstatements. For MRK, the central risk is Keytruda concentration: the drug accounts for roughly half of total company revenue, and its primary U.S.

Growth-minded investors who believe the theme has years to run tend to accept the richer multiple for more upside; value-minded investors lean toward the cheaper forward earnings and steadier profile. Pick ABT if you believe its drivers more; MRK if you believe its. Many investors hold both, but since they share themes, that is a concentrated bet, not diversification. Decide deliberately and check overlap. For the full detail, see the ABT and MRK guides.

ABT. ABT's trailing GAAP P/E of roughly 26x sits below its own 3-year, 5-year, and 10-year historical averages, and is modestly above the Medical Devices and Instruments industry median of roughly 25x, suggesting the market has re-rated the stock from COVID-era growth-premium levels while still assigning a quality multiple. Revenue growth has remained consistently positive in the 5-7% range even as GAAP EPS was pressured in FY2025 by a year-over-year comparison that included elevated one-time items. The FY2026 adjusted EPS guidance of $5.38-$5.58 implies a forward adjusted P/E in the high-teens to low-twenties range at recent share prices, which analysts broadly describe as modestly discounted relative to fundamental fair value estimates.

MRK. Merck's trailing P/E of roughly 34.9x sits about 43 percent above its own 10-year median of 24.4x and above the drug manufacturers industry median of approximately 20.6x, reflecting a market that is pricing in continued Keytruda momentum and pipeline optionality rather than near-term earnings compression. The elevated multiple is somewhat counterintuitive given the 2028 patent cliff, but can be read as the market assigning value to the post-cliff pipeline and the subcutaneous Keytruda lifecycle extension. On an EPS-excluding-acquisition-charges basis, the stock's forward valuation looks more moderate, and GuruFocus rates MRK as fairly valued with a GF Value estimate of approximately $118.

Headline figures (approximate, 2026-06-27 (TTM through Q1 2026; share price data as of June 26, 2026)): ABT shows revenue (ttm) ~$45.1 billion, revenue (fy 2025) ~$44.3 billion (+5.7% YoY), net income (fy 2025) ~$6.5 billion, net profit margin (fy 2025) ~14.7%; MRK shows revenue (fy 2025) ~$65.0 billion, net income (fy 2025) ~$18.3 billion, diluted eps (fy 2025, gaap) ~$7.28, gross margin (fy 2025) ~74.8%.

ABT and MRK are related but distinct: same themes, different businesses and risks. Neither wins in the abstract; the right pick is whichever thesis you actually believe, sized so you are not over-concentrated in one theme. Walnut can show your combined ABT and MRK exposure against your real portfolio. It is not an investment adviser.