Myriad Genetics, Inc. (MYGN) Stock Price & How to Invest

Last updated October 2026

Short answer

Myriad Genetics (MYGN) is a Salt Lake City molecular diagnostics lab that sells hereditary cancer, prostate cancer, prenatal and mental health tests. It is a turnaround story, not a growth story: revenue is shrinking, it lost money in the first half of 2026, and the stock fell about 46% after a July guidance cut. The October 20 deal to sell prenatal testing to Labcorp for $210 million is the first concrete step toward a smaller, oncology-focused company.

MYGN stock price

As of 2026-10-23, Myriad Genetics, Inc. (MYGN) last closed at $5.80, down 28.0% over the past year. Over the past 52 weeks it has traded between $2.86 and $8.18.

MYGN last close
$5.80
1 day
+0.61%
1 month
+44.51%
1 year
-28.01%
52-week range
$2.86 to $8.18
Last close
2026-10-23

Prices are daily closing prices from Yahoo Finance and may be delayed. For the live quote, check your broker or Myriad Genetics, Inc.'s investor relations page. Walnut is informational, not investment advice.

What does Myriad Genetics, Inc. (MYGN) do?

Myriad Genetics runs a high-complexity laboratory business built on genetic and genomic tests. It reports three franchises. Cancer Care Continuum is the largest at ~$114 million of second-quarter 2026 revenue, anchored by the MyRisk hereditary cancer panel, Prolaris for prostate cancer, EndoPredict for breast cancer, MyChoice CDx (a companion diagnostic for PARP inhibitors) and the newer Precise MRD test that looks for residual cancer DNA in blood. Prenatal Health (~$40 million in the quarter) sells Prequel, Foresight, SneakPeek and FirstGene. Mental Health (~$37 million) is GeneSight, a pharmacogenomic test that helps clinicians choose psychiatric medications. Myriad is paid per test, mostly by commercial insurers and Medicare, so the price it collects matters as much as the number of tests it runs.

That is where 2026 went wrong. Second-quarter revenue fell ~11% year over year to ~$190.7 million, even though total volume dipped only ~1%, because average revenue per test fell ~9%. About $11 million of that came from lower than expected collections on older claims, including a ~$4 million write-off of aged receivables. Management cut full-year revenue guidance to $770 to $790 million, suspended adjusted EBITDA guidance, and launched an efficiency program called Ascend. The stock lost about 46% in the following session and spent most of September and early October between roughly $4.00 and $4.60. On October 20 Myriad agreed to sell its Prenatal Health business to Labcorp for $210 million in cash plus inventory value, with closing expected in early 2027, and shares rose more than 20% to around $5.50. The deal price equals roughly half of Myriad's ~$403 million market value before the news. The investment picture is now a test of whether a smaller Myriad, with more cash and fewer distractions, can turn volume growth in hereditary cancer, Prolaris and MRD into revenue growth and positive cash flow. At roughly 0.6x trailing sales, the market is pricing in a lot of doubt about that outcome.

What's driving Myriad Genetics, Inc. (MYGN)?

1. The Labcorp prenatal sale

The $210 million cash sale of Prequel, Foresight, SneakPeek and FirstGene is the main reason MYGN is trending today. Labcorp expects the assets to produce about $160 million of first-year revenue, so Myriad gives up roughly a fifth of its sales, but it was the weakest piece: prenatal revenue fell ~16% in the second quarter and volume fell ~9%. The cash, which would more than double the ~$115 million on the balance sheet at June 30, could cover the ~$121 million of long-term debt or fund oncology launches. The deal carries a $10.5 million reverse termination fee and is expected to close in early 2027, so regulatory or timing slippage remains possible.

2. Hereditary cancer volume versus price

Hereditary cancer testing is the core franchise, and its volume is still growing: second-quarter 2026 tests rose ~8% year over year, with MyRisk up ~10%. Revenue from the same business fell ~13%, though, because the price collected per test dropped. The swing factor for the next few quarters is whether average revenue per test stabilizes once the one-time collection adjustments roll off. If it does, volume growth in the high single digits would start showing up as revenue growth again. If pricing keeps sliding, Myriad is running faster to stand still, which is roughly what the market assumes at ~0.6x sales.

3. Prostate cancer and the AI push

Prolaris, which estimates how aggressive a prostate tumor is, grew volume ~12% in the fourth quarter of 2025 and is the franchise analysts most often point to. Myriad launched Prolaris + AI in mid-2026, and on October 8 it announced work with SOPHiA GENETICS and AstraZeneca to develop a prostate genomic instability score built on the MyChoice CDx platform as a potential companion diagnostic. Companion diagnostic status can lock a test into a drug's prescribing path, which tends to support pricing. These programs are early, and their revenue contribution in 2026 and 2027 is likely to be small compared with the existing Prolaris and MyRisk base.

4. Precise MRD and cost discipline

Precise MRD is Myriad's entry into minimal residual disease testing, the fastest growing corner of cancer diagnostics. It expanded to colorectal and renal cancers in 2026, and a breast cancer coverage request was submitted to MolDX, Medicare's molecular diagnostics program. A favorable coverage decision would be a meaningful catalyst because Medicare reimbursement drives adoption. Alongside that, the Ascend program, supported by an outside consulting firm, aims to cut costs after adjusted EBITDA swung to a ~$17 million loss in the second quarter from a ~$15 million profit a year earlier. Third-quarter results on November 4, 2026 are the next checkpoint for both.

What are the risks to Myriad Genetics, Inc. (MYGN)?

Reimbursement is the central risk. Myriad's revenue fell ~11% in the second quarter on nearly flat volume, which shows how sensitive it is to what payers actually pay. CMS's proposed 2027 Clinical Laboratory Fee Schedule includes cuts of up to ~15% on some codes Myriad uses; one analyst called the impact minimal, but the final numbers are not set. GeneSight lost UnitedHealthcare coverage in 2025, a reminder that a single payer decision can hit a franchise. The company is losing money: the first half of 2026 produced a ~$77 million GAAP net loss and ~$21 million of negative adjusted EBITDA, with cash down from ~$150 million to ~$115 million in six months. Competition in hereditary testing and MRD comes from larger, better funded labs. The prenatal sale may not close, or may close late, and losing ~$160 million of revenue makes the remaining company smaller and more concentrated. Law firms announced investigations after the July guidance cut; these are solicitations, not filed suits, but they can become one. The stock is highly volatile, with more than 40 daily moves above 5% in the past year.

What is the Myriad Genetics, Inc. (MYGN) forecast?

8 analysts publish price targets on MYGN, averaging $4.11 against a $5.73 price as of October 2026, or -28.3%. The published targets run from $2.00 to $8.00, a wide spread, and the ratings split 1 buy, 5 hold, 3 sell. Over the last six months there have been 2 raises and 7 cuts among the published actions. A price target is what an analyst published on a date, not a prediction, and sell-side ratings skew positive across the whole market.

Read the full MYGN forecast and price target for the target table, the recent rating actions by firm, and how the consensus has shifted.

Is MYGN a buy or a sell?

We give no verdict on Myriad Genetics, Inc.. Both cases are real, which is why the question is contested at all, so here is the strongest version of each.

The case for buying. The Labcorp prenatal sale. The $210 million cash sale of Prequel, Foresight, SneakPeek and FirstGene is the main reason MYGN is trending today. The most optimistic published target, $8.00, assumes this works close to its best case.

The case against. Reimbursement is the central risk. The most pessimistic target, $2.00, is roughly what MYGN is worth if this bites instead.

Read the full bull and bear case on MYGN, including what would have to change to break either one. Walnut is not an investment adviser.

How is Myriad Genetics, Inc. (MYGN) valued? (approximate, October 2026)

A simple financial snapshot. These are approximations and refresh quarterly; for current figures see Myriad Genetics, Inc.'s investor relations page or your broker.

  • Revenue (TTM): ~$807 million
  • 2026 revenue guidance: $770 to $790 million
  • Net loss (first half 2026): ~$77 million
  • Adjusted gross margin (Q2 2026): ~67%
  • Market cap (Oct 20, 2026): ~$0.5 billion
  • Price to sales (TTM): ~0.6x

Myriad trades at a fraction of its sales because the market doubts the revenue base is stable. Trailing revenue of ~$807 million combines full-year 2025 revenue of ~$824.5 million with a weaker first half of 2026. There are no meaningful earnings to value: GAAP and adjusted results are both negative in 2026. Cash of ~$115 million roughly offsets ~$121 million of long-term debt, so enterprise value is close to market value. The $210 million Labcorp proceeds, if the deal closes, would equal roughly 40% of the post-announcement market value.

Who competes with Myriad Genetics, Inc. (MYGN)?

Large hereditary and oncology labs

Labcorp (which bought Invitae's assets in 2024 and is now buying Myriad's prenatal unit), Quest Diagnostics and Ambry Genetics (owned by Tempus AI) compete with MyRisk for hereditary cancer panels. They have broader menus and bigger sales forces, which pressures pricing for any single-test specialist.

Cancer genomics and MRD specialists

Natera (Signatera), Guardant Health (Reveal) and Tempus AI are well ahead of Precise MRD in residual disease testing. Veracyte's Decipher test competes with Prolaris in prostate cancer risk stratification. These rivals are larger, growing faster and have more Medicare coverage already in place.

Prenatal and pharmacogenomics players

Natera leads noninvasive prenatal testing, which is part of why Myriad's prenatal unit shrank and is being sold. In mental health, Genomind and broader pharmacogenomic panels from large labs compete with GeneSight, while payer coverage decisions often matter more than any rival's product.

What stocks are similar to Myriad Genetics, Inc. (MYGN)?

Other names that sit close to MYGN: same theme, named as a direct competitor, or held beside it in the same funds. Each entry says which. Worth a look if you are thinking about diversification within a thesis rather than concentration on one ticker.

How to invest in Myriad Genetics, Inc. (MYGN)

There are three common ways to get MYGN exposure. Buy shares (or fractional shares) directly at any major broker. Hold an ETF that includes it, which spreads the position across many companies. Or build it into a focused thematic portfolio, so MYGN sits alongside other stocks that express the same thesis.

Walnut takes the portfolio route. Describe a thesis where MYGN fits (for example “AI infrastructure” or “dividend-growth large-caps”) and the AI proposes 5 to 6 constituents with target weights. You review the plan and fund it through your own broker when you're ready.

New to this? Start with how to invest in stocks, see how to analyze a stock with AI, or compare the best AI stock analyzers.

The bottom line on Myriad Genetics, Inc. (MYGN)

MYGN is a cheap, shrinking diagnostics lab trying to reinvent itself around cancer testing. The Labcorp sale adds cash and focus, but reimbursement pressure and losses still define the story.

More on Myriad Genetics, Inc. (MYGN)

Whether MYGN is worth buying today depends more on your time horizon and what you already hold than on any single call. We walk through valuation, what would have to go right, and the risks in is MYGN a buy or a sell?, and where the stock could go from here in the MYGN stock forecast.

For income investors, whether MYGN pays a dividend and how the payout looks is covered in does MYGN pay a dividend? And to weigh MYGN against a peer, read the full side-by-side comparisons: MYGN vs LH and MYGN vs DGX.

Wondering how MYGN fits the portfolio you already own? Walnut is an AI investing app that connects your brokerage read-only and answers questions like that about your actual holdings: overlap, concentration, and how each position tracks the S&P 500. Compare the best AI portfolio analyzers or see the best AI investing apps in 2026.

Investing in Myriad Genetics, Inc. with AI

Connect the broker you already use and ask Walnut's AI how MYGN fits what you actually hold: whether you own it already through a fund, what it would do to your concentration, and how it has tracked the S&P 500. Read-only by default, and you approve anything before it reaches your broker.

FAQ

What does Myriad Genetics do?

+

Myriad runs clinical laboratories that perform genetic and genomic tests ordered by doctors. Its biggest product line is hereditary cancer testing, led by the MyRisk panel, which checks inherited genes linked to breast, ovarian, colon and other cancers. It also sells Prolaris (prostate cancer aggressiveness), EndoPredict (breast cancer recurrence risk), MyChoice CDx (a companion diagnostic that helps identify patients for PARP inhibitor drugs) and Precise MRD, a blood test that looks for traces of cancer after treatment. GeneSight, its mental health test, analyzes genes that affect how patients process psychiatric drugs. Until the Labcorp sale closes it also owns a prenatal business. The company earns money per test, from insurers, Medicare and patients, so both test volume and the average price collected drive revenue.

Why did MYGN stock fall so much in 2026?

+

The biggest drop came after second-quarter results on July 30, 2026. Revenue fell ~11% to ~$190.7 million, adjusted EPS was a loss of ~$0.25, and management cut full-year revenue guidance to $770 to $790 million while suspending adjusted EBITDA guidance. The stock fell about 46% in the next session. What alarmed investors was the cause: test volume was nearly flat, but the average revenue collected per test fell ~9%, including ~$11 million of lower than expected collections on older claims. That raised questions about the reliability of prior guidance, which management had reaffirmed in May. Several law firms announced investigations afterward. Before October's rally the stock was down about 30% for the year and nearly 50% below its November 2025 high of ~$8.18.

Is Myriad Genetics profitable?

+

Not at the moment. In the first half of 2026 Myriad reported a GAAP net loss of ~$77 million and adjusted EBITDA of roughly negative $21 million. The second quarter alone produced a ~$43 million net loss and ~$17 million of negative adjusted EBITDA, versus a ~$15 million adjusted EBITDA profit a year earlier. Operating cash flow was negative ~$8 million in the quarter and adjusted free cash flow was about negative $11 million. The comparison with 2025's GAAP loss can mislead: the second quarter of 2025 included a large goodwill impairment, which is why that period showed a ~$330 million loss. Management's Ascend efficiency program is meant to restore profitability, but it has not published specific savings targets, and adjusted EBITDA guidance remains suspended as of October 2026.

How does the Labcorp deal change Myriad's finances?

+

If it closes as planned in early 2027, Myriad receives $210 million in cash plus inventory value. At June 30, 2026 it held ~$115 million of cash against ~$121 million of long-term debt, so the proceeds would roughly triple its cash and could be used to repay debt, fund oncology launches or absorb losses while the Ascend program works. In exchange, Myriad loses the prenatal franchise, which Labcorp expects to generate about $160 million of revenue in its first year. That would shrink Myriad's annual revenue base to roughly $620 to $640 million. Because prenatal revenue was falling faster than the rest of the company, management argues the remaining business should grow faster and carry better margins. Whether that holds depends on pricing in hereditary cancer and on Precise MRD gaining coverage.

What do analysts say about MYGN?

+

Views are split, which fits a stock that halved in one day. Craig-Hallum, which rates the shares a Buy, raised its price target from $4 to $8 in early October 2026, citing third-quarter execution, the full-year guide and a planned prenatal sale, and said the stock could double over several months. TD Cowen raised its target from $4.00 to $4.50 but kept a Neutral (Hold) rating, pointing to large addressable markets and volume growth while staying cautious on near-term results. On the CMS proposal for 2027 lab fees, which includes cuts of up to ~15% on some Myriad codes, Craig-Hallum estimated the earnings impact as immaterial to minimally negative. Analyst targets are opinions and have often been wrong on this name; Myriad's next results arrive on November 4, 2026.

What is Precise MRD and why does it matter?

+

Precise MRD is Myriad's minimal residual disease test. It is built from a patient's own tumor sequencing and then checks later blood draws for tiny amounts of circulating tumor DNA, which can signal that cancer has returned before scans show it. MRD testing is one of the fastest growing areas in diagnostics, led by Natera's Signatera. In 2026 Myriad expanded Precise MRD to colorectal and renal cancers and submitted a breast cancer coverage request to MolDX, the program that sets Medicare coverage for many molecular tests. Coverage is the gate to meaningful revenue, because without it labs often run tests and get paid little or nothing. Myriad is a late entrant against well funded rivals, so a positive MolDX decision would be an important signal, while a delay would keep MRD a cost rather than a contributor.

What are the biggest risks for Myriad Genetics stock?

+

The first is pricing. Myriad's 2026 revenue decline came mostly from lower collections per test, and proposed 2027 Medicare fee cuts of up to ~15% on some codes add pressure. The second is cash burn: cash fell from ~$150 million to ~$115 million in six months, and the business is losing money until Ascend savings or the Labcorp proceeds arrive. The third is execution risk on the prenatal sale, which is not expected to close until early 2027. The fourth is competition from larger labs such as Natera, Labcorp, Quest and Tempus, which can bundle tests and outspend Myriad. Finally, the stock is extremely volatile, with more than 40 daily moves above 5% over the past year, so short-term price action can swing far from fundamentals. Walnut is not an investment adviser; this is a description, not advice.

Walnut is informational, not investment advice. Financial figures on this page are approximations; always verify current numbers with Myriad Genetics, Inc.'s investor relations page or your broker before making investment decisions.