Repligen Corporation (RGEN) Stock Price & How to Invest

Last updated October 2026

Short answer

RGEN is Repligen Corporation, a bioprocessing life-sciences supplier whose filtration, chromatography, protein and process-analytics products help drugmakers manufacture biologics. It is a growth-oriented picks-and-shovels play on biologic drug production that trades at a premium multiple (about 14 times trailing sales and ~66 times forward earnings as of October 16, 2026), and it just closed its acquisition of cell and gene therapy supplier BioLife Solutions. Most investors weigh its recovery in organic growth, and now the BioLife integration, against that rich valuation.

RGEN stock price

As of 2026-10-16, Repligen Corporation (RGEN) last closed at $175.42, up 15.0% over the past year. Over the past 52 weeks it has traded between $102.87 and $194.57.

RGEN last close
$175.42
1 day
-4.75%
1 month
+1.45%
1 year
+14.95%
52-week range
$102.87 to $194.57
Last close
2026-10-16

Prices are daily closing prices from Yahoo Finance and may be delayed. For the live quote, check your broker or Repligen Corporation's investor relations page. Walnut is informational, not investment advice.

What does Repligen Corporation (RGEN) do?

Repligen Corporation makes consumable products and equipment used to manufacture biologic drugs, including monoclonal antibodies, gene therapies and vaccines. Its portfolio spans four franchises: filtration (KrosFlo and XCell ATF systems), chromatography resins and columns, proteins (notably Protein A ligands used to purify antibodies), and process analytics. Because roughly 80% of its offerings face limited direct competition and its consumables are embedded in customers' validated manufacturing processes, Repligen sells into a durable, recurring bioprocessing demand base rather than one-off equipment cycles.

The investment picture is one of recovery from the post-pandemic bioprocessing destocking slump. In Q1 2026 revenue rose 15% as reported and 11% organic, with China sales doubling and analytics surging, prompting management to raise adjusted EPS guidance. Q2 2026 followed with revenue of ~$204 million (up ~12% year over year) and adjusted EPS of $0.54 against a ~$0.45 estimate, Repligen's fourth straight quarterly beat. Trailing-twelve-month revenue is now ~$785 million, while GAAP net income of ~$42 million is far thinner than adjusted figures because of amortization and other charges.

On October 6, 2026 Repligen completed its acquisition of BioLife Solutions, a supplier of cell processing tools and biopreservation media (its CryoStor media supports 18 approved therapies), paying $11.25 in cash plus 0.1442 Repligen shares for each BioLife share, a deal reported at about $1.5 billion when announced. Management said it would quantify the effect on its 2026 outlook on the Q3 call on October 27, 2026; consensus for that quarter sits near $0.46 of EPS on ~$207 million of revenue, and analysts model ~$1.08 billion of revenue for 2027 as BioLife is folded in. The shares closed at $175.35 on October 16, 2026, up ~7% year to date and ~13.5% over one year (and ~28% over three months), for a market cap of ~$11.1 billion. The debate for investors still centers on valuation: at roughly 14 times trailing sales and ~66 times forward earnings, the shares price in a sustained return to double-digit growth.

What's driving Repligen Corporation (RGEN)?

1. Bioprocessing recovery and organic reacceleration

After a multi-year destocking correction, Repligen returned to double-digit organic growth in early 2026 (11% organic in Q1, then ~12% reported growth in Q2) with broad-based strength across franchises and geographies. Recovering order patterns from biopharma customers and a doubling of China revenue signal that the inventory overhang has largely cleared. Sustained double-digit organic growth is the central pillar supporting the premium valuation.

2. New modalities and consumables mix

Gene therapy, cell therapy and mRNA manufacturing lean heavily on filtration and analytics, areas where Repligen holds differentiated technology. A growing share of consumables (resins, membranes, ligands) tied to installed equipment creates recurring, higher-margin revenue. As approved biologics scale into commercial production, per-batch consumable pull-through rises.

3. Margin expansion and disciplined M&A

Repligen delivered roughly 160 basis points of adjusted operating margin expansion in Q1 2026 and raised its adjusted EBITDA margin guidance toward the low-20s. The company has a history of bolt-on acquisitions (such as the 908 Devices analytics portfolio) that broaden its franchises, alongside pruning like the March 2026 Polymem divestiture. Improving profitability lifted the 2026 adjusted EPS outlook to roughly $1.97 to $2.05 at the Q1 report; current consensus for 2026 is ~$2.06, and analysts expect ~$2.67 in 2027.

4. BioLife Solutions and cell and gene therapy

The BioLife acquisition, closed on October 6, 2026, is Repligen's largest step into cell and gene therapy workflows. BioLife sells cell processing tools and biopreservation media, and its CryoStor product supports 18 commercially approved therapies, which adds consumables that sit early in the cell therapy process alongside Repligen's filtration and analytics lines. BioLife holders received $11.25 in cash and 0.1442 Repligen shares per share. Repligen has not yet quantified the revenue or earnings contribution; it plans to update its 2026 outlook on the October 27 call, so integration and dilution are open questions for now.

5. Secular biologics manufacturing demand

Long-term biologic and biosimilar volumes are expected to keep growing, and Repligen sits upstream as a supplier to nearly every major drug manufacturer and CDMO. This picks-and-shovels position means the company benefits from industry-wide production growth without exposure to any single drug's clinical outcome. That breadth underpins the durability of the demand base.

What are the risks to Repligen Corporation (RGEN)?

Repligen trades at a rich valuation (around 14 times trailing sales and ~66 times forward earnings in October 2026), so any stumble in organic growth or guidance can trigger sharp multiple compression. The business is cyclical and sensitive to biopharma capital spending, funding conditions for smaller biotech customers, and inventory destocking, all of which hurt results in 2023 to 2024. Concentration among large pharma and CDMO customers, exposure to China and global tariff or trade policy, and integration risk from acquisitions add uncertainty, now sharpened by the BioLife deal: cell therapy is a smaller, more volatile end market than antibodies, the stock portion of the consideration added to Repligen's share count, and the deal's effect on 2026 guidance was still undisclosed as of mid-October. Competition from far larger rivals like Danaher's Cytiva and Sartorius could pressure pricing in overlapping product lines. Finally, as an equipment and consumables supplier, revenue can be lumpy quarter to quarter.

What is the Repligen Corporation (RGEN) forecast?

20 analysts publish price targets on RGEN, averaging $197.95 against a $175.42 price as of October 2026, or +12.8%. The published targets run from $145.00 to $235.00, a moderate spread, and the ratings split 18 buy, 4 hold, 0 sell. Over the last six months there have been 6 raises and 2 cuts among the published actions. A price target is what an analyst published on a date, not a prediction, and sell-side ratings skew positive across the whole market.

Read the full RGEN forecast and price target for the target table, the recent rating actions by firm, and how the consensus has shifted.

Is RGEN a buy or a sell?

We give no verdict on Repligen Corporation. Both cases are real, which is why the question is contested at all, so here is the strongest version of each.

The case for buying. Bioprocessing recovery and organic reacceleration. After a multi-year destocking correction, Repligen returned to double-digit organic growth in early 2026 (11% organic in Q1, then ~12% reported growth in Q2) with broad-based strength across franchises and geographies. The most optimistic published target, $235.00, assumes this works close to its best case.

The case against. Repligen trades at a rich valuation (around 14 times trailing sales and ~66 times forward earnings in October 2026), so any stumble in organic growth or guidance can trigger sharp multiple compression. The most pessimistic target, $145.00, is roughly what RGEN is worth if this bites instead.

Read the full bull and bear case on RGEN, including what would have to change to break either one. Walnut is not an investment adviser.

Has Repligen Corporation (RGEN) split its stock?

No. Repligen Corporation (RGEN) has not split its stock in the last 10 years. That is a statement about the window we check rather than about the company’s entire history, so an older split is possible. It also matters less than it once did: fractional shares mean a high price per share no longer keeps smaller investors out, which removed most of the practical reason to split.

How is Repligen Corporation (RGEN) valued? (approximate, October 2026)

A simple financial snapshot. These are approximations and refresh quarterly; for current figures see Repligen Corporation's investor relations page or your broker.

  • Revenue (TTM): ~$785M
  • Q2 2026 revenue growth: ~12% YoY (~$204M)
  • Q2 2026 adjusted EPS: ~$0.54 (vs ~$0.45 est.)
  • Net income (TTM, GAAP): ~$42M (~5% margin)
  • P/E (trailing / forward): ~240x / ~66x
  • Price/sales: ~14x
  • Market cap: ~$11.1B

As of October 16, 2026, Repligen trades near 14 times trailing sales and ~66 times forward earnings, a premium even among life-science tools names; the ~240x trailing GAAP P/E reflects thin reported profit rather than the adjusted figures management guides to. The shares have climbed ~28% over three months on steady earnings beats, and the next leg of the debate turns on how much the BioLife deal adds to 2027 revenue (consensus ~$1.08 billion) and at what margin.

Which ETFs hold Repligen Corporation (RGEN)?

If you want RGEN exposure as part of a larger bundle rather than directly, these ETFs hold it meaningfully. Weights are approximate and refresh quarterly.

ETFName% in RGENExpense ratio
FBTFirst Trust NYSE Arca Biotechnology Index Fund4.07%0.55%

Who competes with Repligen Corporation (RGEN)?

Large diversified bioprocessing giants

Danaher (through its Cytiva and Pall brands), Sartorius (Sartorius Stedim Biotech), Merck KGaA (MilliporeSigma) and Thermo Fisher Scientific are far larger suppliers of filtration, chromatography and single-use systems. They compete in Repligen's overlapping product lines and hold much deeper resources, though Repligen differentiates on specialized filtration and analytics technology.

Specialized filtration and chromatography peers

Smaller specialists in tangential-flow filtration, resins, columns and process analytics compete for niche portions of the workflow. Repligen argues roughly 80% of its offerings face limited direct competition thanks to differentiated technology like KrosFlo and XCell ATF, but new entrants and in-house customer development are ongoing threats.

What stocks are similar to Repligen Corporation (RGEN)?

Other names that sit close to RGEN: same theme, named as a direct competitor, or held beside it in the same funds. Each entry says which. Worth a look if you are thinking about diversification within a thesis rather than concentration on one ticker.

How to invest in Repligen Corporation (RGEN)

There are three common ways to get RGEN exposure. Buy shares (or fractional shares) directly at any major broker. Hold an ETF that includes it (FBT), which spreads the position across many companies. Or build it into a focused thematic portfolio, so RGEN sits alongside other stocks that express the same thesis.

Walnut takes the portfolio route. Describe a thesis where RGEN fits (for example “AI infrastructure” or “dividend-growth large-caps”) and the AI proposes 5 to 6 constituents with target weights. You review the plan and fund it through your own broker when you're ready.

New to this? Start with how to invest in stocks, see how to analyze a stock with AI, or compare the best AI stock analyzers.

The bottom line on Repligen Corporation (RGEN)

Repligen is a high-quality, high-multiple bioprocessing supplier whose story hinges on whether reaccelerating organic growth, plus the newly closed BioLife Solutions deal, can justify a valuation of roughly 14 times trailing sales; third-quarter results on October 27, 2026 are the first chance to see management's updated outlook.

More on Repligen Corporation (RGEN)

Whether RGEN is worth buying today depends more on your time horizon and what you already hold than on any single call. We walk through valuation, what would have to go right, and the risks in is RGEN a buy or a sell?, and where the stock could go from here in the RGEN stock forecast.

For income investors, whether RGEN pays a dividend and how the payout looks is covered in does RGEN pay a dividend? And to weigh RGEN against a peer, read the full side-by-side comparisons: RGEN vs DHR and RGEN vs TMO.

Wondering how RGEN fits the portfolio you already own? Walnut is an AI investing app that connects your brokerage read-only and answers questions like that about your actual holdings: overlap, concentration, and how each position tracks the S&P 500. Compare the best AI portfolio analyzers or see the best AI investing apps in 2026.

Investing in Repligen Corporation with AI

Connect the broker you already use and ask Walnut's AI how RGEN fits what you actually hold: whether you own it already through a fund, what it would do to your concentration, and how it has tracked the S&P 500. Read-only by default, and you approve anything before it reaches your broker.

FAQ

What company is RGEN?

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RGEN is the Nasdaq ticker for Repligen Corporation, a Massachusetts-based bioprocessing company that supplies filtration, chromatography, protein and process-analytics products used to manufacture biologic drugs like antibodies and gene therapies.

What does Repligen actually sell?

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Repligen sells consumables and equipment across four franchises: filtration (KrosFlo and XCell ATF systems), chromatography resins and columns, proteins including Protein A ligands used to purify antibodies, and process analytics instruments. Its products are embedded in drugmakers' manufacturing lines.

Is Repligen profitable?

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Yes. Repligen is profitable on both a GAAP and adjusted basis, though GAAP profit is thin: trailing net income is about $42 million on ~$785 million of revenue. On an adjusted basis it guided full-year 2026 EPS to roughly $1.97 to $2.05 at the Q1 report, Q2 adjusted EPS came in at $0.54 against a ~$0.45 estimate, and current consensus for 2026 is ~$2.06.

How fast is Repligen growing?

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In Q1 2026 revenue grew about 15% as reported and 11% organically as the bioprocessing market recovered from a destocking slump, and Q2 2026 revenue rose about 12% to ~$204 million. Consensus calls for ~$833 million of 2026 revenue and ~$1.08 billion in 2027, the latter including the BioLife Solutions acquisition that closed in October 2026.

Why is RGEN considered expensive?

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At a market cap around $11.1 billion on trailing revenue near $785 million (October 16, 2026), Repligen trades at roughly 14 times sales and ~66 times forward earnings. That premium multiple prices in sustained double-digit growth, so the valuation leaves little room for disappointment relative to slower-growing industrial peers.

Who competes with Repligen?

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Its largest competitors are diversified bioprocessing giants: Danaher (Cytiva and Pall), Sartorius, Merck KGaA (MilliporeSigma) and Thermo Fisher Scientific. Repligen contends that about 80% of its offerings face limited direct competition thanks to differentiated filtration and analytics technology.

What are the main risks for RGEN investors?

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Key risks include its rich valuation and vulnerability to multiple compression, cyclical biopharma capital spending, customer destocking, China and tariff exposure, customer concentration among large pharma and CDMOs, competition from much larger rivals, and integration of the BioLife Solutions acquisition closed in October 2026. Quarterly results can also be lumpy given equipment sales.

What is the BioLife Solutions acquisition?

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Repligen completed its purchase of BioLife Solutions on October 6, 2026. BioLife supplies cell processing tools and biopreservation media for cell and gene therapy, and its CryoStor media supports 18 commercially approved therapies. Each BioLife share was exchanged for $11.25 in cash plus 0.1442 Repligen shares, in a deal reported at about $1.5 billion when announced. Repligen said it would detail the effect on its 2026 outlook with third-quarter results on October 27, 2026.

How has RGEN stock performed in 2026?

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Repligen closed at $175.35 on October 16, 2026, up about 7% year to date and about 13.5% over one year. Most of the gain came recently: the shares rose roughly 28% over three months and hit a 52-week high near $198.87 in late September, against a 52-week low of about $101. The average analyst target is near $198, with a consensus rating of strong buy across 20 analysts. Walnut is not an investment adviser.

How can I invest in RGEN?

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Repligen trades on the Nasdaq under the ticker RGEN and can be bought through any standard brokerage account. Some investors hold it as part of a thematic basket focused on life-science tools or biologics manufacturing rather than as a standalone position. Walnut is not an investment adviser.

Walnut is informational, not investment advice. Financial figures on this page are approximations; always verify current numbers with Repligen Corporation's investor relations page or your broker before making investment decisions.