MIR vs TMO: Which Is the Better Buy in 2026?
Last updated September 2026
Short answer
TMO is the larger of the two ($222.03B market cap): the incumbent the market prices for continued execution (21.85x forward earnings, beta 0.85). MIR is the smaller challenger ($3.86B), priced similarly on forward earnings (23.11x): more room to run, but more to prove. The real question is which set of drivers you believe, and whether owning one (or both) leaves you over-concentrated.
MIR vs TMO: the tie-breaker metrics
Same yardstick, side by side (as of September 2026). Valuation lined up like this is most meaningful for two names in the same corner of the market, which these are. Figures are approximate; verify before investing.
| Metric | MIR | TMO | What it tells you |
|---|---|---|---|
| Market cap | $3.86B | $222.03B | Size. The larger name is the incumbent; the smaller has more room to grow and more to prove. |
| Forward P/E | 23.11 | 21.85 | Valuation on next year's expected earnings, the same yardstick for both. Lower is cheaper for that growth; higher means the market is paying up. |
| Trailing P/E | 172.33 | 32.35 | Valuation on the last 12 months. A big drop from trailing to forward means the market expects earnings to jump, so more growth is already in the price. |
| Beta | 1.06 | 0.85 | Volatility vs the market. Above 1 swings harder than the index; below 1 is steadier. Higher beta means bigger drawdowns to hold through. |
| Price vs 52-week range | 9% of range | 78% of range | Where today's price sits between the 52-week low and high. Near the high is momentum with less margin of safety; near the low is out of favor or a discount, depending on why. |
| Price / book | 2.07 | 4.21 | How much you pay over book value. Very high can signal an asset-light, high-return business or a rich price. |
Before you buy: how MIR and TMO affect your concentration
The metrics above tell you which is the marginally better business. The bigger risk for most people is not picking the slightly worse stock, it is over-concentrating. MIR and TMO share themes, so owning both, or adding either to what you already hold, can quietly push a large share of your portfolio into one bet.
This is the part a generic comparison page cannot answer, because it depends on what you own. Connect your brokerage and Walnut shows your real, combined MIR and TMO exposure, flags overlap with your existing positions, and tells you if adding one would tip you past a concentration you are comfortable with, read-only by default, with your login staying at your broker. Walnut is not an investment adviser.
What does Mirion Technologies (MIR) do?
Mirion Technologies (NYSE: MIR) designs and sells radiation detection, measurement, analysis and monitoring products across two segments: Nuclear & Safety, which serves nuclear power plants, defense, research labs and industrial customers, and Medical, which supports cancer-care delivery, medical diagnostics and practitioner radiation safety. The company came public through a 2021 SPAC merger and describes itself as the only pure-play public company of its scale in radiation measurement, giving investors combined exposure to the nuclear energy revival and advanced medical applications. Much of its value sits in a large installed base of equipment, dosimetry services and recurring aftermarket revenue.
What does Thermo Fisher Scientific (TMO) do?
Thermo Fisher Scientific, headquartered in Waltham, Massachusetts, is a global provider of scientific instruments, consumables, reagents, and services used across pharmaceutical and biotech drug development, clinical diagnostics, academic research, and environmental and industrial testing. The company operates through four reportable segments: Life Sciences Solutions (reagents, proteins, and consumables for research and bioproduction), Analytical Instruments (mass spectrometers, chromatography systems, electron microscopes, and laboratory equipment), Specialty Diagnostics (clinical diagnostic kits and transplant diagnostics), and Laboratory Products and Biopharma Services (supply-chain distribution, contract research through PPD, and contract drug manufacturing through Patheon). Revenue is generated through instrument sales, high-margin consumables and reagents that customers repurchase continuously, long-term service contracts, and growing contract development and manufacturing (CDMO) fees; consumables and services collectively account for a majority of annual sales and provide durable recurring revenue.
MIR vs TMO: how do they differ?
Both fit overlapping themes, but they are not interchangeable. The useful comparison is which set of drivers and risks you want exposure to.
- MIR drivers: Nuclear power tailwind; Backlog and recurring revenue.
- TMO drivers: Bioprocessing and Biologic Drug Manufacturing Tailwind; Recurring Consumables and Reagents Engine.
Which fits which kind of investor
A faster-growing, richer-valued name usually swings harder, so it suits a longer horizon and a higher tolerance for volatility; a steadier, more cash-generative business suits a more conservative or income-minded investor. The honest test is which set of risks you could hold through a drawdown: Mirion has a history of GAAP net losses, and reported earnings remain thin relative to its valuation, so much of the story depends on adjusted figures. For TMO, the most significant near-term risk is a contraction in research funding from government agencies (including NIH) and from biotech companies whose access to capital markets has historically been cyclical; when funding tightens, customers delay instrument purchases and reduce consumable orders, pressuring organic revenue growth.
MIR or TMO: which should you pick?
Growth-minded investors who believe the theme has years to run tend to accept the richer multiple for more upside; value-minded investors lean toward the cheaper forward earnings and steadier profile. Pick MIR if you believe its drivers more; TMO if you believe its. Many investors hold both, but since they share themes, that is a concentrated bet, not diversification. Decide deliberately and check overlap. For the full detail, see the MIR and TMO guides.
MIR vs TMO: the full fundamentals
MIR. Mirion trades as a growth-oriented industrial where adjusted EBITDA and free cash flow, not GAAP EPS, anchor most valuation work given ongoing net losses and heavy interest costs. Backlog above $1.1 billion and double-digit order growth support the multiple, but roughly $1.2 billion of debt keeps leverage in focus. Reported figures vary by source and date, so confirm current numbers before relying on them.
TMO. Thermo Fisher's trailing price-to-earnings ratio of roughly 26x sits approximately 18% below its own ten-year historical average of about 32x, reflecting a period of softer organic growth as the post-pandemic diagnostics and COVID-related revenue tailwind has faded. The adjusted operating margin of 22.7% for 2025 and management guidance for 6 to 8 percent adjusted EPS growth in 2026 suggest the earnings recovery is progressing, though the pace of organic revenue acceleration remains a key variable the market is watching. Free cash flow of roughly $6.3 billion gives the company significant flexibility for continued share repurchases, dividends, and acquisitions.
Headline figures (approximate, JULY 2026): MIR shows revenue (fy2025) ~$925M, revenue (q1 2026) ~$258M (+27.5% YoY), 2026 rev growth guidance ~22% to 24%, 2026 adj. ebitda guidance ~$285M to $300M; TMO shows revenue (full year 2025) ~$44.6 billion, revenue guidance (full year 2026) ~$46.3 to $47.2 billion, adjusted operating income (full year 2025) ~$10.1 billion, adjusted operating margin (full year 2025) ~22.7%.
The bottom line: MIR vs TMO
MIR and TMO are related but distinct: same themes, different businesses and risks. Neither wins in the abstract; the right pick is whichever thesis you actually believe, sized so you are not over-concentrated in one theme. Walnut can show your combined MIR and TMO exposure against your real portfolio. It is not an investment adviser.
Wondering how MIR or TMO fits the portfolio you already own? Walnut is an AI investing app that connects your brokerage read-only and answers questions like that about your actual holdings: overlap, concentration, and how each position tracks the S&P 500. Compare the best AI portfolio analyzers or see the best AI investing apps in 2026.
Investing in Mirion Technologies with AI
Connect the broker you already use and ask Walnut's AI how MIR fits what you actually hold: whether you own it already through a fund, what it would do to your concentration, and how it has tracked the S&P 500. Read-only by default, and you approve anything before it reaches your broker.
FAQ
What is the difference between MIR and TMO?
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Mirion Technologies (NYSE: MIR) designs and sells radiation detection, measurement, analysis and monitoring products across two segments: Nuclear & Safety, which serves nuclear power plants, defense, research labs and industrial customers, and Medical, which supports cancer-care delivery, medical diagnostics and practitioner radiation safety. Thermo Fisher Scientific, headquartered in Waltham, Massachusetts, is a global provider of scientific instruments, consumables, reagents, and services used across pharmaceutical and biotech drug development, clinical diagnostics, academic research, and environmental and industrial testing. They show up together because they share investment themes, but they are different businesses, so the better fit depends on which thesis you are expressing.
Is MIR or TMO the better stock?
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Neither is universally better. TMO is the larger incumbent; MIR is the smaller challenger and looks pricier on forward earnings. Walnut is informational, not investment advice. Compare what each does, the tie-breaker metrics above, and the risks, then decide which fits your thesis and what you already own.
Which is cheaper, MIR or TMO?
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On forward P/E (as of September 2026), MIR trades at 23.11x and TMO at 21.85x, so TMO is the cheaper of the two on next year's expected earnings. A lower multiple is not automatically the better buy: a richer valuation can be justified by faster growth, and a lower one can reflect real risk. Weigh the multiple against how fast each business is compounding.
Should you own both MIR and TMO?
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Because they share themes, owning both concentrates you in that theme. That can be intentional (a focused bet) or accidental (less diversification than it looks). Walnut can show your combined exposure across both, and whether adding either over-concentrates you, before you buy.
What are the risks of MIR vs TMO?
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MIR: Mirion has a history of GAAP net losses, and reported earnings remain thin relative to its valuation, so much of the story depends on adjusted figures. The balance sheet carries meaningful debt (around $1.2 billion) and interest expense, which pressures net income and adds sensitivity to rates. Growth leans on acquisitions, creating integration, goodwill and execution risk. Nuclear project timing can be lumpy and dependent on government funding and utility capital budgets, and a large share of revenue ties to a niche end market. The shares have been volatile, down meaningfully year to date at points in 2026 even after strong quarterly orders. TMO: The most significant near-term risk is a contraction in research funding from government agencies (including NIH) and from biotech companies whose access to capital markets has historically been cyclical; when funding tightens, customers delay instrument purchases and reduce consumable orders, pressuring organic revenue growth. Thermo Fisher's active acquisition strategy carries integration and leverage risk, particularly after committing approximately $13 billion to mergers and acquisitions in 2025 alone, and a large deal that underperforms expectations could weigh on earnings and the balance sheet simultaneously. Geopolitical friction, particularly regarding China, creates both a demand risk (softer orders from Chinese academic and industrial customers) and a supply chain risk, while tariff policy changes can disrupt cost structures. Finally, the stock's valuation, though below its own ten-year average on a trailing price-to-earnings basis, still prices in sustained mid-single-digit organic growth, leaving limited room for disappointment if end markets soften.
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Walnut is informational, not investment advice. This page is descriptive and not a recommendation to buy or sell MIR or TMO; figures are approximate and dated (as of September 2026). Verify current data before investing.